Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.54 |
| ▸ | GAA | P10253 | 8/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | EED | O75530 | 1/20 | 0.44 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1391074 | 0.79 | MAPT (0.72) | KDM4EALDH1A1GAAHPGDMAPK1 | |
| SCHEMBL2805209 | 0.78 | ALDH1A1 (0.68) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL14433848 | 0.78 | RAB9A (0.69) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL9528898 | 0.78 | ALDH1A1 (0.70) | KDM4EALDH1A1GAAHPGDMAPK1 | |
| SCHEMBL4392903 | 0.78 | KCNH3 (0.51) | KDM4EALDH1A1MAPK1NPSR1MAPT | |
| SCHEMBL11792458 | 0.77 | SMN1; SMN2 (0.59) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL456092 | 0.77 | GAA (0.58) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL26644710 | 0.77 | KDM4E (0.58) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL10657204 | 0.77 | ALDH1A1 (0.60) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL15455447 | 0.77 | ALDH1A1 (0.54) | KDM4EALDH1A1GAAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020124500-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 江苏凯迪恩医药科技有限公司 | 2020-06-25 | — | — | WO | disclosed |
| WO-2020124500-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 江苏凯迪恩医药科技有限公司 | 2020-06-25 | — | — | WO | disclosed |