Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | HTT | P42858 | 4/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | GAA | P10253 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14433848 | 0.84 | RAB9A (0.69) | ALDH1A1HTTHPGDSMN1; SMN2MAPT | |
| SCHEMBL5506600 | 0.83 | ALDH1A1 (0.78) | ALDH1A1LMNAHTTHPGDGPR174 | |
| SCHEMBL5445694 | 0.83 | ALDH1A1 (1.00) | ALDH1A1LMNAHTTHPGDGPR174 | |
| SCHEMBL13805297 | 0.82 | ALDH1A1 (1.00) | ALDH1A1LMNAHTTHPGDGPR174 | |
| SCHEMBL22621288 | 0.82 | GPR174 (1.00) | ALDH1A1LMNAHTTHPGDGPR174 | |
| SCHEMBL3634965 | 0.79 | SMN1; SMN2 (1.00) | ALDH1A1LMNAHTTHPGDGPR174 | |
| SCHEMBL22129202 | 0.78 | KDM4E (0.54) | ALDH1A1LMNAHTTHPGDSMN1; SMN2 | |
| SCHEMBL11273843 | 0.77 | POLB (1.00) | ALDH1A1LMNAHTTHPGDGPR174 | |
| SCHEMBL9529930 | 0.77 | MAOB (0.71) | ALDH1A1LMNAHPGDSMN1; SMN2MAPT | |
| SCHEMBL5448009 | 0.77 | KMT2A (0.79) | ALDH1A1LMNAHTTHPGDGPR174 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |