Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2211615 | 0.88 | ALOX5 (0.41) | PKMPTGS2PTGS1KDM4EGAA | |
| SCHEMBL2213832 | 0.86 | PKM (0.38) | PKMPTGS2PTGS1KDM4EGAA | |
| SCHEMBL5748233 | 0.83 | ALOX5 (0.34) | ALDH1A1CA2TDP1LMNAPPARG | |
| SCHEMBL5750215 | 0.83 | RARG (0.40) | PKMPTGS2PTGS1KDM4EGAA | |
| SCHEMBL2268666 | 0.76 | RXRA (0.40) | PKMKDM4EGAAALDH1A1KMT2A | |
| SCHEMBL1354887 | 0.71 | MAPT (0.46) | PKMPTGS2KDM4EGAAALDH1A1 | |
| SCHEMBL9363323 | 0.69 | MAPT (0.40) | PKMPTGS2PTGS1KDM4EGAA | |
| SCHEMBL2211640 | 0.66 | MAPT (0.34) | PKMKDM4EALDH1A1CA12CA1 | |
| SCHEMBL5749454 | 0.66 | ALOX5 (0.42) | PKMKDM4EGAAALDH1A1KMT2A | |
| SCHEMBL27563989 | 0.65 | TDP1 (0.45) | PKMPTGS2PTGS1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1952843-B1 | Photostable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom | MERCK PATENT GMBH (DE) | 2011-07-27 | — | — | EP | disclosed |
| EP-1747773-B1 | Photostable organic sunscreen compositions with antioxidant properties | MERCK PATENT GMBH (DE) | 2010-08-04 | — | — | EP | disclosed |
| EP-1952843-A1 | Photostable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom | Merck Patent GmbH (DE) | 2008-08-06 | — | — | EP | disclosed |
| EP-1747773-A2 | Photostable organic sunscreen compositions with antioxidant properties | Merck Patent GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| EP-1406582-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GMBH (DE) | 2006-10-25 | — | — | EP | disclosed |