Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 12/20 | 0.40 |
| ▸ | PPARG | P37231 | 10/20 | 0.40 |
| ▸ | RARG | P13631 | 7/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 3/20 | 0.32 |
| ▸ | RXRG | P48443 | 3/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2211615 | 0.88 | ALOX5 (0.41) | RXRAPPARGRARGSMPD1ALOX5 | |
| SCHEMBL2213744 | 0.76 | PKM (0.35) | RXRAPPARGRARGSMPD1ALOX5 | |
| SCHEMBL2213832 | 0.72 | PKM (0.38) | SMPD1ALOX5MCL1KDM4EALDH1A1 | |
| SCHEMBL5750215 | 0.70 | RARG (0.40) | RXRAPPARGRARGMCL1KDM4E | |
| SCHEMBL5748233 | 0.68 | ALOX5 (0.34) | PPARGALOX5ALDH1A1 | |
| SCHEMBL5749454 | 0.66 | ALOX5 (0.42) | SMPD1ALOX5NFKB1NFKB2RELA | |
| SCHEMBL2211640 | 0.64 | MAPT (0.34) | RXRAPPARGRARGSMPD1MCL1 | |
| SCHEMBL28238937 | 0.60 | CA1 (0.45) | SMPD1ALOX5NFKB1THRBKDM4E | |
| SCHEMBL2290699 | 0.60 | KDM4E (0.51) | ALOX5PDE4DKDM4EALDH1A1GAA | |
| SCHEMBL9363323 | 0.59 | MAPT (0.40) | RXRAPPARGRARGSMPD1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406582-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GMBH (DE) | 2006-10-25 | — | — | EP | claimed |
| EP-1635777-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GMBH (DE) | 2012-06-06 | — | — | EP | disclosed |
| US-8003082-B2 | Photostable organic sunscreen composition | MERCK PATENT GMBH (DE) | 2011-08-23 | — | — | US | disclosed |
| EP-1747773-B1 | Photostable organic sunscreen compositions with antioxidant properties | MERCK PATENT GMBH (DE) | 2010-08-04 | — | — | EP | disclosed |
| EP-1952843-A1 | Photostable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom | Merck Patent GmbH (DE) | 2008-08-06 | — | — | EP | disclosed |
| EP-1747773-A2 | Photostable organic sunscreen compositions with antioxidant properties | Merck Patent GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| US-7166273-B2 | Photo stable organic sunscreen compositions | EMD CHEMICALS, INC. (US) | 2007-01-23 | — | — | US | disclosed |
| EP-1406582-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GMBH (DE) | 2006-10-25 | — | — | EP | disclosed |
| EP-1635777-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| US-6831191-B2 | Blocking ultraviolet radiation on skin | EM INDUSTRIES | 2004-12-14 | — | — | US | disclosed |
| WO-2004105712-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GMBH (DE) | 2004-12-09 | — | — | WO | disclosed |
| US-20040247536-A1 | Photo stable organic sunscreen compositions | EMD CHEMICALS, INC. | 2004-12-09 | — | — | US | disclosed |
| EP-1406582-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GmbH (DE) | 2004-04-14 | — | — | EP | disclosed |
| US-20030157035-A1 | PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | EM INDUSTRIES | 2003-08-21 | — | — | US | disclosed |
| WO-2003007906-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GMBH (DE) | 2003-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030157035-A1 | PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | ERCC1, ERCC4, OGG1 | RXRA 2602/4885PPARG 3754/4885RARG 1191/4885 |
| US-20040247536-A1 | Photo stable organic sunscreen compositions | SUN2, CCNB1, TYR | RXRA 902/4885PPARG 1470/4885RARG 239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.