Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2213744 | 0.86 | PKM (0.35) | PKMPTGS2PTGS1KDM4EGAA | |
| SCHEMBL2211615 | 0.84 | ALOX5 (0.41) | PKMPTGS2PTGS1KDM4EGAA | |
| SCHEMBL5748233 | 0.81 | ALOX5 (0.34) | CA2LMNATDP1CYP3A4ALDH1A1 | |
| SCHEMBL5750215 | 0.81 | RARG (0.40) | PKMPTGS2PTGS1KDM4EGAA | |
| SCHEMBL9363323 | 0.79 | MAPT (0.40) | PKMPTGS2PTGS1KDM4EGAA | |
| SCHEMBL2211640 | 0.79 | MAPT (0.34) | PKMKDM4ECA12CA1CA2 | |
| SCHEMBL1260575 | 0.76 | HMGCR (0.41) | PKMPTGS2KDM4EGAACA12 | |
| SCHEMBL3360767 | 0.76 | HMGCR (0.40) | PKMPTGS2PTGS1CA12CA1 | |
| SCHEMBL2394283 | 0.72 | PKM (0.54) | PKMPTGS2PTGS1KDM4EGAA | |
| SCHEMBL2268666 | 0.72 | RXRA (0.40) | PKMKDM4EGAAALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406582-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GMBH (DE) | 2006-10-25 | — | — | EP | claimed |
| EP-1635777-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GMBH (DE) | 2012-06-06 | — | — | EP | disclosed |
| US-8003082-B2 | Photostable organic sunscreen composition | MERCK PATENT GMBH (DE) | 2011-08-23 | — | — | US | disclosed |
| EP-1952843-B1 | Photostable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom | MERCK PATENT GMBH (DE) | 2011-07-27 | — | — | EP | disclosed |
| EP-1747773-B1 | Photostable organic sunscreen compositions with antioxidant properties | MERCK PATENT GMBH (DE) | 2010-08-04 | — | — | EP | disclosed |
| EP-1952843-A1 | Photostable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom | Merck Patent GmbH (DE) | 2008-08-06 | — | — | EP | disclosed |
| US-20070059258-A1 | Photostable organic sunscreen composition | MERCK PATENT GMBH (DE) | 2007-03-15 | — | — | US | disclosed |
| EP-1747773-A2 | Photostable organic sunscreen compositions with antioxidant properties | Merck Patent GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| US-7166273-B2 | Photo stable organic sunscreen compositions | EMD CHEMICALS, INC. (US) | 2007-01-23 | — | — | US | disclosed |
| EP-1406582-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GMBH (DE) | 2006-10-25 | — | — | EP | disclosed |
| EP-1635777-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004105712-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GMBH (DE) | 2004-12-09 | — | — | WO | disclosed |
| US-20040247536-A1 | Photo stable organic sunscreen compositions | EMD CHEMICALS, INC. | 2004-12-09 | — | — | US | disclosed |
| EP-1406582-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GmbH (DE) | 2004-04-14 | — | — | EP | disclosed |
| US-6602515-B2 | Alpha-acetyl-3,5-dimethoxy-4-hydroxy cinnamate ester; dipalmitoyl-3,5- dimethoxy-4-hydroxy benzylidene malonate or amide derivatives | EM INDUSTRIES | 2003-08-05 | — | — | US | disclosed |
| US-20030108492-A1 | PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | EM INDUSTRIES | 2003-06-12 | — | — | US | disclosed |
| WO-2003007906-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GMBH (DE) | 2003-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070059258-A1 | Photostable organic sunscreen composition | SUN2, ERCC1, PPOX | PKM 3156/4885PTGS2 788/4885PTGS1 1285/4885 |
| US-20030108492-A1 | PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | ERCC1, ERCC4, OGG1 | PKM 730/4885PTGS2 1659/4885PTGS1 1319/4885 |
| US-20040247536-A1 | Photo stable organic sunscreen compositions | SUN2, CCNB1, TYR | PKM 3841/4885PTGS2 2617/4885PTGS1 3341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.