Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.50 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | JAK1 | P23458 | 1/20 | 0.50 |
| ▸ | TYK2 | P29597 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ASPH | Q12797 | 2/20 | 0.49 |
| ▸ | RIOX2 | Q8IUF8 | 2/20 | 0.49 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10322346 | 0.91 | KDM4E (0.56) | JAK3IRAK4JAK2JAK1TYK2 | |
| SCHEMBL22140401 | 0.86 | JAK3 (0.51) | JAK3IRAK4JAK2JAK1TYK2 | |
| SCHEMBL4402491 | 0.85 | JAK3 (0.50) | JAK3IRAK4JAK2JAK1TYK2 | |
| SCHEMBL29743221 | 0.85 | JAK3 (0.50) | JAK3IRAK4JAK2JAK1TYK2 | |
| SCHEMBL28798922 | 0.78 | KDM4E (0.59) | KDM4EASPHRIOX2KDM8MAPT | |
| SCHEMBL29656721 | 0.78 | KDM4E (0.59) | KDM4EASPHRIOX2KDM8MAPT | |
| SCHEMBL1523353 | 0.77 | KDM4C (0.62) | KDM4EHTR6ALDH1A1HPGDCRHBP | |
| SCHEMBL10322813 | 0.77 | HTR6 (0.66) | JAK3KDM4EHTR6ALDH1A1RAB9A | |
| SCHEMBL22854454 | 0.76 | ALDH1A1 (0.68) | KDM4EHTR6MAPTALDH1A1HPGD | |
| SCHEMBL21723070 | 0.75 | KDM4E (0.56) | KDM4EASPHRIOX2KDM8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127243-A1 | COMPOUND FOR USE IN RETINAL DISEASES | ZHUHAI UNITED LABORATORIES CO., LTD. (CN) | 2022-04-28 | — | — | US | disclosed |
| EP-3901138-A1 | COMPOUND FOR USE IN RETINAL DISEASES | Medshine Discovery Inc. (CN) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020125659-A1 | COMPOUND FOR USE IN RETINAL DISEASES | 南京明德新药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127243-A1 | COMPOUND FOR USE IN RETINAL DISEASES | ALDH1A2, ALDH1A3, NR2E3 | JAK3 4856/4885IRAK4 4160/4885JAK2 4824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.