Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474353 | 0.82 | HTR6 (0.51) | HTR6 | |
| SCHEMBL20929543 | 0.81 | HTR6 (0.55) | HTR6ASIC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22144444 | 0.80 | DDB1 (0.53) | HTR6ASIC3F10DRD2DRD3 | |
| SCHEMBL30201617 | 0.80 | DDB1 (0.53) | HTR6ASIC3F10DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL25431522 | 0.79 | DDB1 (0.51) | HTR6ASIC3F10DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL29507046 | 0.79 | DDB1 (0.51) | HTR6ASIC3F10DRD2DRD3 | |
| SCHEMBL15939888 | 0.77 | TSHR (0.47) | HTR6PARP1 | |
| SCHEMBL8262713 | 0.76 | ALDH1A1 (0.49) | HTR6SLC6A2SLC6A4SLC6A3PARP1 | |
| SCHEMBL25405394 | 0.75 | PNMT (0.47) | HTR6ASIC3DRD2DRD3 | |
| SCHEMBL30801297 | 0.75 | ASIC3 (0.47) | HTR6ASIC3DRD2DRD3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132561-A1 | TARGETED PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |