Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.51 |
| ▸ | HTR2C | P28335 | 9/20 | 0.43 |
| ▸ | HTR2B | P41595 | 7/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15939888 | 0.89 | TSHR (0.47) | HTR6 | |
| SCHEMBL22144682 | 0.82 | HTR6 (0.46) | HTR6 | |
| SCHEMBL7478863 | 0.74 | NR1H2 (0.54) | — | |
| SCHEMBL20929543 | 0.74 | HTR6 (0.55) | HTR6 | |
| SCHEMBL24380324 | 0.74 | BCAT2 (0.53) | HTR6HTR2CHTR2BHTR2A | |
| SCHEMBL22144444 | 0.73 | DDB1 (0.53) | HTR6 | |
| SCHEMBL26684149 | 0.73 | DDB1 (0.53) | HTR6 | |
| SCHEMBL30450133 | 0.73 | DDB1 (0.53) | HTR6 | |
| SCHEMBL30201617 | 0.73 | DDB1 (0.53) | HTR6 | |
| SCHEMBL11492352 | 0.72 | CYP11B2 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | claimed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | claimed |
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | disclosed |