SCHEMBL22148673

SCHEMBL22148673

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4c(-n5c6ccccc6c6cc(-c7ccc8c(c7)c7ccccc7n8-c7ccccc7)ccc65)c(-n5c6ccccc6c6ccccc65)nc(-n5c6ccccc6c6ccccc65)c4-n4c5ccccc5c5cc(-c6ccc7c(c6)c6ccccc6n7-c6ccccc6)ccc54)cc3)n2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
ATM Q13315 2/20 0.43
KDM4E B2RXH2 1/20 0.43
PTGER4 P35408 2/20 0.38
KMT2A Q03164 4/20 0.38
ABCG2 Q9UNQ0 4/20 0.34
NPY5R Q15761 2/20 0.33
TSPO P30536 1/20 0.33
IL1R1 P14778 1/20 0.33
MEN1 O00255 3/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
HTT P42858 1/20 0.32
HPGD P15428 1/20 0.32
RAC2 P15153 1/20 0.32
RAC3 P60763 1/20 0.32
CDC42 P60953 1/20 0.32
RAC1 P63000 1/20 0.32
ACP1 P24666 1/20 0.31
AVPR1A P37288 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22457797 0.95 L3MBTL1 (0.43) L3MBTL1ATMKDM4EPTGER4KMT2A
SCHEMBL22148653 0.94 TSPO (0.37) L3MBTL1ATMKDM4EPTGER4KMT2A
SCHEMBL22148639 0.92 ATM (0.37) L3MBTL1ATMKDM4EPTGER4KMT2A
SCHEMBL21562743 0.91 L3MBTL1 (0.51) L3MBTL1ATMKDM4EPTGER4KMT2A
SCHEMBL22148642 0.90 MEN1 (0.36) L3MBTL1ATMKDM4EKMT2ATSPO
SCHEMBL22457853 0.90 KDM4E (0.40) L3MBTL1ATMKDM4EPTGER4KMT2A
SCHEMBL21888655 0.89 NPY5R (0.37) L3MBTL1ATMKDM4EPTGER4KMT2A
SCHEMBL21562746 0.89 TSPO (0.40) L3MBTL1ATMKDM4EPTGER4KMT2A
SCHEMBL21562745 0.89 TSPO (0.40) L3MBTL1ATMKDM4EPTGER4KMT2A
SCHEMBL21085320 0.89 KMT2A (0.38) L3MBTL1ATMKDM4EKMT2AABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200203622-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES KYULUX, INC. (JP) 2020-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200203622-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES NDUFV3, NDUFV2, CRY2 L3MBTL1 1938/4885ATM 2778/4885KDM4E 4409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.