Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22149075 | 0.91 | IRAK4 (0.40) | IRAK4PDPK1 | |
| SCHEMBL22149145 | 0.80 | RXRA (0.34) | SMN1; SMN2KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL22148990 | 0.79 | IDO1 (0.35) | IRAK4MAPT | |
| SCHEMBL22149083 | 0.79 | SLC22A12 (0.38) | IRAK4GCGRTSHRSMN1; SMN2KDM4E | |
| SCHEMBL22149086 | 0.78 | IRAK4 (0.51) | IRAK4PDPK1NPC1RAB9ATDP1 | |
| SCHEMBL22149104 | 0.76 | SRC (0.40) | GCGRSMN1; SMN2 | |
| SCHEMBL22148994 | 0.75 | MET (0.51) | — | |
| SCHEMBL22149101 | 0.75 | KDR (0.43) | — | |
| SCHEMBL22149088 | 0.74 | DOT1L (0.37) | SMN1; SMN2KDM4ELMNAMAPTHSD17B10 | |
| SCHEMBL22149082 | 0.74 | MET (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |