Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.36 |
| ▸ | AXL | P30530 | 2/20 | 0.36 |
| ▸ | MERTK | Q12866 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 10/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.33 |
| ▸ | LCLAT1 | Q6UWP7 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22129173 | 0.79 | IDO1 (0.40) | METAXLMERTKIDO1MAPT | |
| SCHEMBL22129172 | 0.78 | ALOX15 (0.48) | METAXLIDO1MAPTGSK3B | |
| SCHEMBL22149069 | 0.78 | MAPT (0.37) | METAXLMERTKIDO1MAPT | |
| SCHEMBL22149303 | 0.76 | IDO1 (0.41) | METAXLMERTKIDO1MAPT | |
| SCHEMBL22129170 | 0.69 | JMJD6 (0.36) | IDO1MAPTGSK3BCYP3A4RET | |
| SCHEMBL22129178 | 0.67 | JMJD6 (0.39) | METIDO1MAPTGSK3BCYP3A4 | |
| SCHEMBL22148987 | 0.67 | MGLL (0.41) | IDO1CYP3A4 | |
| SCHEMBL22148990 | 0.66 | IDO1 (0.35) | METAXLMERTKIDO1MAPT | |
| SCHEMBL22149067 | 0.66 | ABCB1 (0.44) | IDO1MAPTCYP3A4MAPK1SRC | |
| SCHEMBL26317945 | 0.64 | SLC2A1 (0.51) | METKDM4EMAPK1NPSR1DDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |