Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22129173 | 0.86 | IDO1 (0.40) | HTTKDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL22149303 | 0.85 | IDO1 (0.41) | METMAPTGSK3BAXLIDO1 | |
| SCHEMBL6301162 | 0.84 | ALOX15 (0.57) | ALOX15HTTKDM4EKDM6BKDM5C | |
| SCHEMBL22149069 | 0.80 | MAPT (0.37) | ALOX15HTTMETMAPTGSK3B | |
| SCHEMBL22129178 | 0.80 | JMJD6 (0.39) | ALOX15METMAPTGSK3BJMJD6 | |
| SCHEMBL22149079 | 0.78 | MET (0.36) | KDM4EMETMAPTGSK3BAXL | |
| SCHEMBL6298726 | 0.77 | ALOX15 (0.56) | ALOX15HTTKDM4EKDM6BKDM5C | |
| SCHEMBL31734085 | 0.77 | ALOX15 (0.56) | ALOX15HTTKDM4EKDM6BKDM5C | |
| SCHEMBL22129170 | 0.77 | JMJD6 (0.36) | MAPTGSK3BJMJD6IDO1CYP3A4 | |
| SCHEMBL2716634 | 0.76 | LMNA (0.50) | HTTMAPTCYP2C9CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111670182-A | Quinoline derivatives, preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2020-09-15 | — | — | CN | disclosed |
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |