Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 7/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22129172 | 0.80 | ALOX15 (0.48) | JMJD6MAPTGSK3BALOX15IDO1 | |
| SCHEMBL22129170 | 0.78 | JMJD6 (0.36) | JMJD6MAPTGSK3BMGLLRET | |
| SCHEMBL22129173 | 0.76 | IDO1 (0.40) | MAPTGSK3BIDO1ALDH1A1CYP3A4 | |
| SCHEMBL22149303 | 0.75 | IDO1 (0.41) | MAPTGSK3BIDO1CYP3A4MET | |
| SCHEMBL22148989 | 0.75 | ABCB1 (0.35) | JMJD6MGLLIDO1CSF1RPDGFRB | |
| SCHEMBL22149069 | 0.73 | MAPT (0.37) | JMJD6MAPTGSK3BALOX15RET | |
| SCHEMBL22149067 | 0.72 | ABCB1 (0.44) | JMJD6MAPTKMT2AMGLLIDO1 | |
| SCHEMBL22148987 | 0.72 | MGLL (0.41) | JMJD6MGLLIDO1CYP3A4 | |
| SCHEMBL11653261 | 0.69 | MAPT (0.50) | MAPTALOX15KMT2AALDH1A1 | |
| SCHEMBL22149079 | 0.67 | MET (0.36) | MAPTGSK3BRETIDO1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111670182-A | Quinoline derivatives, preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2020-09-15 | — | — | CN | disclosed |
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |