Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 4/20 | 0.37 |
| ▸ | MET | P08581 | 4/20 | 0.37 |
| ▸ | MERTK | Q12866 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22149058 | 0.92 | MGLL (0.39) | MGLLAXLMETMERTKAR | |
| SCHEMBL22149092 | 0.89 | MGLL (0.39) | MGLLAXLMETMERTKTGFBR1 | |
| SCHEMBL22149000 | 0.88 | KDR (0.36) | MGLLGCKAXLMETMERTK | |
| SCHEMBL22149094 | 0.88 | PDGFRA (0.41) | MGLLAXLMETMERTKKDR | |
| SCHEMBL22149065 | 0.88 | MET (0.49) | MGLLAXLMETMERTKKDR | |
| SCHEMBL22149103 | 0.86 | TGFBR1 (0.38) | MGLLAXLMETMERTKTGFBR1 | |
| SCHEMBL22149002 | 0.85 | MGLL (0.41) | MGLLAXLMETMERTKTGFBR1 | |
| SCHEMBL22149061 | 0.84 | GPBAR1 (0.37) | MGLLAXLMETMERTKTGFBR1 | |
| SCHEMBL22149106 | 0.83 | MGLL (0.41) | MGLLTGFBR1KDRIDO1 | |
| SCHEMBL22148987 | 0.83 | MGLL (0.41) | MGLLARIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |