SCHEMBL22149094 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	PDGFRA	P16234	2/20	0.41

▸	AXL	P30530	9/20	0.40

▸	MGLL	Q99685	1/20	0.40

▸	MET	P08581	11/20	0.39

▸	MERTK	Q12866	2/20	0.39

▸	KDR	P35968	2/20	0.38

▸	KIT	P10721	1/20	0.38

▸	FLT3	P36888	1/20	0.38

▸	MST1R	Q04912	1/20	0.38

▸	IDO1	P14902	2/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL22149058	0.92	MGLL (0.39)	AXLMGLLMETMERTKIDO1
SCHEMBL22149065	0.90	MET (0.49)	PDGFRAAXLMGLLMETMERTK
SCHEMBL22149093	0.88	MGLL (0.39)	PDGFRAAXLMGLLMETMERTK
SCHEMBL22148998	0.87	PDGFRA (0.44)	PDGFRAAXLMETMERTKKDR
SCHEMBL22149103	0.86	TGFBR1 (0.38)	AXLMGLLMETMERTKKDR
SCHEMBL22149002	0.85	MGLL (0.41)	AXLMGLLMETMERTKKDR
SCHEMBL22149061	0.85	GPBAR1 (0.37)	AXLMGLLMETMERTKKDR
SCHEMBL22149084	0.84	MGLL (0.37)	PDGFRAAXLMGLLMETMERTK
SCHEMBL22149092	0.82	MGLL (0.39)	AXLMGLLMETMERTKKDR
SCHEMBL22148987	0.81	MGLL (0.41)	MGLLIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2020124515-A1	QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF	东莞市东阳光农药研发有限公司	2020-06-25	—	—	WO	disclosed