Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | RORB | Q92753 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22148997 | 0.86 | PGR (0.38) | PIM3ALDH1A1PGRRORARORC | |
| SCHEMBL22149135 | 0.85 | MEN1 (0.35) | PIM3ALPLALPGKDM4ENPC1 | |
| SCHEMBL22145138 | 0.83 | KDM4E (0.38) | ALDH1A1GAAKDM4EMAPTPABPC1 | |
| SCHEMBL22145137 | 0.78 | L3MBTL1 (0.37) | ALDH1A1KDM4EMAPTATMPOLB | |
| SCHEMBL22148960 | 0.77 | PGR (0.34) | PGRRORARORCRORBMAPT | |
| SCHEMBL22145196 | 0.76 | — | — | |
| SCHEMBL22145200 | 0.74 | — | — | |
| SCHEMBL24336133 | 0.74 | KDM4E (0.41) | PIM3ALDH1A1PGRRORARORC | |
| SCHEMBL22145128 | 0.73 | KDM4E (0.38) | ALDH1A1GAAKDM4EMAPTPABPC1 | |
| SCHEMBL26289924 | 0.73 | KDM4E (0.33) | ALDH1A1KDM4EMAPTATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898590-B1 | METHOD FOR PREPARING INDOLENAPHTHOPYRANS | TRANSITIONS OPTICAL LTD (IE) | 2023-11-22 | — | — | EP | disclosed |
| US-20220073533-A1 | Method for Preparing Indolenaphthopyrans | TRANSITIONS OPTICAL, LTD. (IE) | 2022-03-10 | — | — | US | disclosed |
| WO-2020126033-A1 | METHOD FOR PREPARING INDOLENAPHTHOPYRANS | TRANSITIONS OPTICAL, LTD. (IE) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020126029-A1 | ARTICLES COMPRISING INDOLENAPHTHOPYRANS | TRANSITIONS OPTICAL, LTD. (IE) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220073533-A1 | Method for Preparing Indolenaphthopyrans | CCNH, CCNT1, PAH | PIM3 386/4885ALDH1A1 1459/4885PGR 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.