Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.35 |
| ▸ | MYLK | Q15746 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22149102 | 0.85 | PIM3 (0.41) | MEN1KMT2ACNR2PIM3ALPL | |
| SCHEMBL22148960 | 0.85 | PGR (0.34) | MEN1KMT2ADYRK1A | |
| SCHEMBL23919144 | 0.83 | KDM4E (0.35) | MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL23919130 | 0.82 | MAPT (0.36) | MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL22148997 | 0.78 | PGR (0.38) | DYRK1ACNR2PIM3CNR1 | |
| SCHEMBL22145128 | 0.76 | KDM4E (0.38) | MEN1KMT2AMYLKKDM4EHSD17B10 | |
| SCHEMBL22145250 | 0.76 | KDM4E (0.36) | MEN1KMT2AKDM4EHSD17B10NPC1 | |
| SCHEMBL22145217 | 0.75 | MAT2A (0.39) | — | |
| SCHEMBL22145205 | 0.74 | EDNRA (0.34) | MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL22145135 | 0.74 | EDNRA (0.36) | MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317129-A1 | Indolenaphthopyrans | TRANSITIONS OPTICAL, LTD. (IE) | 2021-10-14 | — | — | US | disclosed |
| WO-2020126029-A1 | ARTICLES COMPRISING INDOLENAPHTHOPYRANS | TRANSITIONS OPTICAL, LTD. (IE) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317129-A1 | Indolenaphthopyrans | AHR, TDO2, TPH2 | MEN1 3107/4885KMT2A 2760/4885SLC6A1 2347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.