Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10304805 | 0.89 | PTGS2 (0.46) | BRD4CREBBPTNKSTNKS2ACHE | |
| SCHEMBL10091244 | 0.85 | PGR (0.44) | BRD4CREBBPTNKSTNKS2AKR1C3 | |
| SCHEMBL12330295 | 0.84 | TNKS (0.57) | BRD4CREBBPTNKSTNKS2AKR1C3 | |
| SCHEMBL19935596 | 0.81 | TNKS (0.54) | BRD4CREBBPTNKSTNKS2AKR1C3 | |
| SCHEMBL10091308 | 0.80 | AKR1C3 (0.42) | BRD4CREBBPTNKSTNKS2AKR1C3 | |
| SCHEMBL16852356 | 0.80 | AKR1C3 (0.47) | BRD4CREBBPTNKSTNKS2AKR1C3 | |
| SCHEMBL17840301 | 0.79 | BRD4 (0.40) | BRD4CREBBPTNKSTNKS2AKR1C3 | |
| SCHEMBL10091242 | 0.78 | WDR5 (0.40) | BRD4CREBBPTNKSTNKS2AKR1C3 | |
| SCHEMBL27363344 | 0.77 | TNKS (0.43) | BRD4CREBBPTNKSTNKS2AKR1C3 | |
| SCHEMBL257771 | 0.77 | MEN1 (0.46) | BRD4CREBBPTNKSTNKS2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200199141-A1 | PSEUDO TRÖGER'S BASE-DERIVED DIANHYDRIDES AND POLYIMIDES DERIVED FROM PSEUDO TRÖGER'S BASE-DERIVED DIANHYDRIDES | UNIV KING ABDULLAH SCI & TECH (SA) | 2020-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200199141-A1 | PSEUDO TRÖGER'S BASE-DERIVED DIANHYDRIDES AND POLYIMIDES DERIVED FROM PSEUDO TRÖGER'S BASE-DERIVED DIANHYDRIDES | PARG, PLEC, TARBP1 | BRD4 614/4885CREBBP 3536/4885TNKS 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.