SCHEMBL22160484

SCHEMBL22160484

CC(=O)OCc1c(F)c(F)c(CO)c(F)c1F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.42
ALDH1A1 P00352 7/20 0.39
HSD17B10 Q99714 2/20 0.36
LMNA P02545 1/20 0.36
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36
MMP12 P39900 1/20 0.36
TDP1 Q9NUW8 3/20 0.34
CYP4F2 P78329 2/20 0.33
CYP4A11 Q02928 2/20 0.33
CYP3A4 P08684 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
GALR3 O60755 1/20 0.31
KDM4E B2RXH2 1/20 0.30
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44341 0.89 CA2 (0.46) CA2ALDH1A1HSD17B10LMNAMMP1
SCHEMBL1786267 0.83 MEN1 (0.43) CA2ALDH1A1HSD17B10LMNAMMP1
SCHEMBL1785282 0.83 CA2 (0.42) CA2ALDH1A1HSD17B10LMNAMMP1
Alcohol SCHEMBL22129229 0.82 CA2 (0.39) CA2ALDH1A1HSD17B10LMNAMMP1
SCHEMBL9785523 0.82 CA2 (0.41) CA2ALDH1A1HSD17B10LMNAMMP1
SCHEMBL22758888 0.78 CA2 (0.41) CA2ALDH1A1HSD17B10LMNAMMP1
Acetic Acid SCHEMBL22129233 0.78 PRKCE (0.36) ALDH1A1TDP1
SCHEMBL13034140 0.78 ALDH1A1 (0.42) CA2ALDH1A1HSD17B10LMNAMMP1
Acetic Acid SCHEMBL28282631 0.77 FFAR3 (0.39) CYP4F2CYP4A11
SCHEMBL356917 0.76 MEN1 (0.35) MMP1MMP2MMP9MMP12TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10745334-B2 Method for synthesizing 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol ZHEJIANG ZHONGXIN FLUORIDE MAT CO LTD (CN) 2020-08-18 US disclosed
US-20200207693-A1 METHOD FOR SYNTHESIZING 2,3,5,6-TETRAFLUORO-4-METHOXYMETHYL BENZYL ALCOHOL ZHEJIANG ZHONGXIN FLUORIDE MAT CO LTD (CN) 2020-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10745334-B2 Method for synthesizing 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol TET2, TH, ALKBH2 CA2 1199/4885ALDH1A1 362/4885HSD17B10 597/4885
US-20200207693-A1 METHOD FOR SYNTHESIZING 2,3,5,6-TETRAFLUORO-4-METHOXYMETHYL BENZYL ALCOHOL TH, ALKBH2, ALKBH3 CA2 1650/4885ALDH1A1 345/4885HSD17B10 512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.