Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL359266 | 0.89 | GCGR (0.39) | GCGRIGF1RSRCAXLPTK2 | |
| Propionic Acid SCHEMBL22160486 | 0.89 | FFAR3 (0.37) | GCGRIMPDH2 | |
| Acetic Acid SCHEMBL28282631 | 0.85 | FFAR3 (0.39) | IMPDH2 | |
| SCHEMBL22160484 | 0.78 | CA2 (0.42) | ALDH1A1TDP1 | |
| SCHEMBL22129223 | 0.78 | MMP1 (0.36) | PRKCEIMPDH2ALDH1A1TDP1IGF1R | |
| SCHEMBL9766130 | 0.78 | RECQL (0.38) | IMPDH2TDP1IGF1RSRCAXL | |
| Alcohol SCHEMBL22129229 | 0.77 | CA2 (0.39) | GCGRALDH1A1TDP1 | |
| SCHEMBL19478317 | 0.76 | CA2 (0.39) | GCGR | |
| SCHEMBL9785635 | 0.76 | CA2 (0.39) | GCGR | |
| SCHEMBL19478240 | 0.76 | GCGR (0.35) | GCGRIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10745334-B2 | Method for synthesizing 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol | ZHEJIANG ZHONGXIN FLUORIDE MAT CO LTD (CN) | 2020-08-18 | — | — | US | disclosed |
| US-20200207693-A1 | METHOD FOR SYNTHESIZING 2,3,5,6-TETRAFLUORO-4-METHOXYMETHYL BENZYL ALCOHOL | ZHEJIANG ZHONGXIN FLUORIDE MAT CO LTD (CN) | 2020-07-02 | — | — | US | disclosed |
| WO-2020124727-A1 | SYNTHESIS METHOD FOR 2,3,5,6-TETRAFLUORO-4-METHOXYMETHYL BENZYL ALCOHOL | 浙江中欣氟材股份有限公司 | 2020-06-25 | — | — | WO | disclosed |
| CN-109438234-B | Synthetic method of 2,3,5, 6-tetrafluoro-4-methoxymethyl benzyl alcohol | 浙江中欣氟材股份有限公司 | 2020-04-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745334-B2 | Method for synthesizing 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol | TET2, TH, ALKBH2 | PRKCE 2413/4885GCGR 4661/4885IMPDH2 1256/4885 |
| US-20200207693-A1 | METHOD FOR SYNTHESIZING 2,3,5,6-TETRAFLUORO-4-METHOXYMETHYL BENZYL ALCOHOL | TH, ALKBH2, ALKBH3 | PRKCE 2302/4885GCGR 4714/4885IMPDH2 1027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.