Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 known ✓ | P03956 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1785282 | 0.94 | CA2 (0.42) | CA2ALDH1A1LMNAHSD17B10MMP1 | |
| SCHEMBL44341 | 0.84 | CA2 (0.46) | CA2ALDH1A1LMNAHSD17B10MMP1 | |
| Alcohol SCHEMBL22160482 | 0.84 | CYP1A2 (0.37) | ALDH1A1HSD17B10MMP1MMP2MMP9 | |
| SCHEMBL22160484 | 0.82 | CA2 (0.42) | CA2ALDH1A1LMNAHSD17B10MMP1 | |
| SCHEMBL22160485 | 0.79 | CYP1A2 (0.36) | ALDH1A1HSD17B10MMP1MMP2MMP9 | |
| SCHEMBL1786267 | 0.79 | MEN1 (0.43) | CA2ALDH1A1LMNAHSD17B10MMP1 | |
| SCHEMBL22129223 | 0.79 | MMP1 (0.36) | ALDH1A1LMNAMMP1MMP2MMP9 | |
| SCHEMBL9785523 | 0.77 | CA2 (0.41) | CA2ALDH1A1LMNAHSD17B10MMP1 | |
| Acetic Acid SCHEMBL22129233 | 0.77 | PRKCE (0.36) | ALDH1A1TDP1GCGR | |
| SCHEMBL27815858 | 0.76 | ALDH1A1 (0.39) | ALDH1A1HSD17B10MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10745334-B2 | Method for synthesizing 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol | ZHEJIANG ZHONGXIN FLUORIDE MAT CO LTD (CN) | 2020-08-18 | — | — | US | disclosed |
| US-20200207693-A1 | METHOD FOR SYNTHESIZING 2,3,5,6-TETRAFLUORO-4-METHOXYMETHYL BENZYL ALCOHOL | ZHEJIANG ZHONGXIN FLUORIDE MAT CO LTD (CN) | 2020-07-02 | — | — | US | disclosed |
| WO-2020124727-A1 | SYNTHESIS METHOD FOR 2,3,5,6-TETRAFLUORO-4-METHOXYMETHYL BENZYL ALCOHOL | 浙江中欣氟材股份有限公司 | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745334-B2 | Method for synthesizing 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol | TET2, TH, ALKBH2 | MMP1 3686/4885CA2 1199/4885ALDH1A1 362/4885 |
| US-20200207693-A1 | METHOD FOR SYNTHESIZING 2,3,5,6-TETRAFLUORO-4-METHOXYMETHYL BENZYL ALCOHOL | TH, ALKBH2, ALKBH3 | MMP1 3587/4885CA2 1650/4885ALDH1A1 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.