Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24653241 | 0.86 | — | — | |
| SCHEMBL21931150 | 0.79 | PDE7A (0.38) | PDE4BPDE7APDE7BCYP2A6 | |
| SCHEMBL22796995 | 0.77 | PDE4A (0.30) | PDE4B | |
| SCHEMBL22797001 | 0.73 | — | — | |
| SCHEMBL22215584 | 0.72 | CYP2A6 (0.32) | CYP2A6 | |
| SCHEMBL22796965 | 0.71 | KDM4E (0.43) | PDE4BPDE7APDE7BCYP2A6 | |
| SCHEMBL18418923 | 0.71 | CYP2A6 (0.30) | CYP2A6 | |
| SCHEMBL22796671 | 0.69 | IRAK4 (0.31) | — | |
| SCHEMBL21594783 | 0.67 | PDE7A (0.33) | PDE7A | |
| SCHEMBL10653657 | 0.67 | MEN1 (0.35) | PDE4BPDE7APDE7BCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230235339-A1 | IMPORT OF UNNATURAL OR MODIFIED NUCLEOSIDE TRIPHOSPHATES INTO CELLS VIA NUCLEIC ACID TRIPHOSPHATE TRANSPORTERS | THE SCRIPPS RESEARCH INSTITUTE | 2023-07-27 | — | — | US | disclosed |
| US-20210341473-A1 | MOLECULAR WIRES FOR DETECTING A BIOLOGICAL OR CHEMICAL ENTITY OR EVENT | Velanidi Technologies LLC | 2021-11-04 | — | — | US | disclosed |
| US-20200392550-A1 | REAGENTS AND METHODS FOR REPLICATION, TRANSCRIPTION, AND TRANSLATION IN SEMI-SYNTHETIC ORGANISMS | THE SCRIPPS RESEARCH INSTITUTE | 2020-12-17 | — | — | US | disclosed |
| US-20200224234-A1 | INCORPORATION OF UNNATURAL NUCLEOTIDES AND METHODS OF USE IN VIVO THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2020-07-16 | — | — | US | disclosed |
| US-10696720-B2 | Nucleoside triphosphate transporter and uses thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230235339-A1 | IMPORT OF UNNATURAL OR MODIFIED NUCLEOSIDE TRIPHOSPHATES INTO CELLS VIA NUCLEIC ACID TRIPHOSPHATE TRANSPORTERS | NUDT1, UPP1, UMPS | PDE4B 3354/4885PDE7A 2460/4885PDE7B 3014/4885 |
| US-10696720-B2 | Nucleoside triphosphate transporter and uses thereof | SLC35B2, SLC29A2, PNP | PDE4B 993/4885PDE7A 581/4885PDE7B 1079/4885 |
| US-20200224234-A1 | INCORPORATION OF UNNATURAL NUCLEOTIDES AND METHODS OF USE IN VIVO THEREOF | NUDT1, DNTT, TRMT1 | PDE4B 3369/4885PDE7A 1971/4885PDE7B 1765/4885 |
| US-20200392550-A1 | REAGENTS AND METHODS FOR REPLICATION, TRANSCRIPTION, AND TRANSLATION IN SEMI-SYNTHETIC ORGANISMS | RNGTT, MAX, POLRMT | PDE4B 4403/4885PDE7A 3519/4885PDE7B 4146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.