Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB2 | P49721 | 9/20 | 0.33 |
| ▸ | PSMB10 | P40306 | 8/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.31 |
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | CPA1 | P15085 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17532335 | 1.00 | PSMB2 (0.33) | PSMB2PSMB10KLKB1KIFC1MME | |
| SCHEMBL17532332 | 0.94 | PSMB2 (0.33) | PSMB2PSMB10KLKB1KIFC1 | |
| SCHEMBL17539189 | 0.93 | KIFC1 (0.35) | PSMB2KIFC1MMEACEACE2 | |
| SCHEMBL22167479 | 0.93 | KIFC1 (0.35) | PSMB2KIFC1MMEACEACE2 | |
| SCHEMBL17459567 | 0.92 | MME (0.32) | PSMB2PSMB10KIFC1MME | |
| SCHEMBL19695848 | 0.92 | MME (0.32) | PSMB2PSMB10KIFC1MME | |
| SCHEMBL17532334 | 0.91 | DGAT1 (0.33) | PSMB2PSMB10 | |
| SCHEMBL17532333 | 0.90 | ENPP2 (0.31) | PSMB2PSMB10 | |
| SCHEMBL17532337 | 0.90 | ANPEP (0.35) | — | |
| SCHEMBL22167260 | 0.89 | L3MBTL1 (0.32) | KLKB1KIFC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |