Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083991 | 0.89 | ESR1 (0.49) | PTGS2KMT2AMAPTMEN1NTSR1 | |
| SCHEMBL17430489 | 0.86 | PTGS2 (0.42) | PTGS2KMT2AMAPTPGRKDM4E | |
| SCHEMBL8089080 | 0.85 | BACE1 (0.47) | KMT2APDE4BMAPTKDM4EMEN1 | |
| SCHEMBL8433324 | 0.83 | ALDH1A1 (0.38) | PTGS2KMT2APDE4BMAPTHTT | |
| SCHEMBL11377638 | 0.83 | PTGS2 (0.40) | PTGS2KMT2AMAPTMEN1TDP1 | |
| SCHEMBL11206138 | 0.83 | PTGS2 (0.37) | PTGS2KMT2AMAPT | |
| SCHEMBL17430478 | 0.82 | CYP19A1 (0.51) | PTGS2KMT2AMAPTHTTKDM4E | |
| SCHEMBL571799 | 0.82 | MAPK1 (0.39) | PTGS2KMT2AMAPTLMNAHTT | |
| SCHEMBL8432224 | 0.81 | ALDH1A1 (0.44) | PTGS2PDE4BMAPTKDM4EALDH1A1 | |
| SCHEMBL11206044 | 0.81 | NR1H2 (0.40) | PTGS2PDE4BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200208007-A1 | STIMULI-RESPONSIVE COLOR-CHANGING FUNCTIONAL COATING, PREPARATION METHOD AND APPLICATION THEREOF | UNIVERSITY OF AKRON | 2020-07-02 | — | — | US | disclosed |
| WO-2012017005-A2 | POLYMERS BASED ON BENZODIONES | BASF SE (DE) | 2012-02-09 | — | — | WO | disclosed |
| US-7737286-B2 | α-Hydroxy-benzeneacetic acid derivatives, and compounds having two 5-membered latone rings fused to central cyclohexa-1,4-diene nucleus based upon the same, and uses of the compounds | KYUNG-IN SYNTHETIC CORPORATION (KR) | 2010-06-15 | — | — | US | disclosed |
| US-7737286-B2 | α-Hydroxy-benzeneacetic acid derivatives, and compounds having two 5-membered latone rings fused to central cyclohexa-1,4-diene nucleus based upon the same, and uses of the compounds | KYUNG-IN SYNTHETIC CORPORATION (KR) | 2010-06-15 | — | — | US | disclosed |
| US-20070220688-A1 | Alpha-Hydroxy-Benzeneacetic Acid Derivatives, and Compounds Having Two 5-Membered Latone Rings Fused to Central Cyclohexa-1,4-Diene Nucleus Based Upon the Same, and Uses of the Compounds | KYUNG-IN SYNTHETIC CORPORATION (KR) | 2007-09-27 | — | — | US | disclosed |
| US-20070220688-A1 | Alpha-Hydroxy-Benzeneacetic Acid Derivatives, and Compounds Having Two 5-Membered Latone Rings Fused to Central Cyclohexa-1,4-Diene Nucleus Based Upon the Same, and Uses of the Compounds | KYUNG-IN SYNTHETIC CORPORATION (KR) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070220688-A1 | Alpha-Hydroxy-Benzeneacetic Acid Derivatives, and Compounds Having Two 5-Membered Latone Rings Fused to Central Cyclohexa-1,4-Diene Nucleus Based Upon the Same, and Uses of the Compounds | LDHA, HCAR1, HPD | PTGS2 2384/4885KMT2A 555/4885PDE4B 3009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.