Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15714789 | 0.91 | MAPK1 (0.41) | MEN1NPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL17517811 | 0.84 | ALDH1A1 (0.39) | MEN1NPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL22170331 | 0.81 | PTGS2 (0.46) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL571799 | 0.78 | MAPK1 (0.39) | MEN1NPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL29544302 | 0.76 | PTGS2 (0.46) | MEN1NPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL17430598 | 0.72 | ALDH1A1 (0.44) | MEN1NPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL17517796 | 0.72 | HPGD (0.40) | MEN1NPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL9270824 | 0.69 | PDE4B (0.41) | MEN1NPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL17432754 | 0.68 | ME2 (0.45) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL22170333 | 0.66 | PTGS2 (0.45) | KMT2AMAPTKDM4ELMNAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012017005-A2 | POLYMERS BASED ON BENZODIONES | BASF SE (DE) | 2012-02-09 | — | — | WO | disclosed |
| WO-2012017005-A2 | POLYMERS BASED ON BENZODIONES | BASF SE (DE) | 2012-02-09 | — | — | WO | disclosed |