Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET3 | O43151 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | FBXL19 | Q6PCT2 | 2/20 | 0.51 |
| ▸ | CXXC5 | Q7LFL8 | 2/20 | 0.51 |
| ▸ | TET1 | Q8NFU7 | 2/20 | 0.51 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.51 |
| ▸ | CXXC4 | Q9H2H0 | 2/20 | 0.51 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 5/20 | 0.46 |
| ▸ | ITK | Q08881 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.46 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26217925 | 0.88 | ACHE (0.46) | TET3KMT2AFBXL19CXXC5TET1 | |
| SCHEMBL22446321 | 0.87 | KMT2A (0.56) | TET3KMT2AFBXL19CXXC5TET1 | |
| SCHEMBL22174135 | 0.86 | EGFR (0.50) | EGFRITKERBB2RYR2EPHX2 | |
| SCHEMBL22174252 | 0.85 | EGFR (0.47) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL26216582 | 0.84 | ADRB2 (0.48) | TET3KMT2AFBXL19CXXC5TET1 | |
| SCHEMBL22173964 | 0.83 | TET3 (0.53) | TET3KMT2AFBXL19CXXC5TET1 | |
| SCHEMBL22174132 | 0.83 | GPR119 (0.50) | KMT2AEGFRERBB2MAPTSMN1; SMN2 | |
| SCHEMBL1196748 | 0.83 | KCNH2 (0.46) | KMT2AMAPTSMN1; SMN2KCNH2MCHR1 | |
| SCHEMBL22174136 | 0.82 | NAAA (0.51) | KMT2AEGFRERBB2SMN1; SMN2EPHX2 | |
| SCHEMBL24168592 | 0.81 | TEAD1 (0.56) | EGFRERBB2EPHX2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11771689-B2 | Cereblon modulators and uses thereof | VIVIDION THERAPEUTICS, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-11771689-B2 | Cereblon modulators and uses thereof | VIVIDION THERAPEUTICS, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-20220298213-A1 | IN VIVO ENGINEERED CEREBLON PROTEIN | VIVIDION THERAPEUTICS, INC. | 2022-09-22 | — | — | US | disclosed |
| US-10869860-B2 | Cereblon modulators and uses thereof | VIVIDION THERAPEUTICS, INC. (US) | 2020-12-22 | — | — | US | disclosed |
| US-20200216507-A1 | IN VIVO ENGINEERED CEREBLON PROTEIN | VIVIDION THERAPEUTICS, INC. | 2020-07-09 | — | — | US | disclosed |
| US-20200206201-A1 | CEREBLON MODULATORS AND USES THEREOF | VIVIDION THERAPEUTICS, INC. | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220298213-A1 | IN VIVO ENGINEERED CEREBLON PROTEIN | CRBN, CDR2, DCUN1D4 | TET3 666/4885KMT2A 607/4885FBXL19 247/4885 |
| US-20200216507-A1 | IN VIVO ENGINEERED CEREBLON PROTEIN | CRBN, CDR2, DCUN1D4 | TET3 666/4885KMT2A 607/4885FBXL19 247/4885 |
| US-11771689-B2 | Cereblon modulators and uses thereof | CRBN, CBFB, CNN2 | TET3 4521/4885KMT2A 3580/4885FBXL19 3394/4885 |
| US-10869860-B2 | Cereblon modulators and uses thereof | CRBN, CBFB, CNN2 | TET3 4521/4885KMT2A 3580/4885FBXL19 3394/4885 |
| US-20200206201-A1 | CEREBLON MODULATORS AND USES THEREOF | CRBN, CBFB, CNN2 | TET3 4521/4885KMT2A 3580/4885FBXL19 3394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.