Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2218213 | 1.00 | HSD11B1 (0.47) | HSD11B1ALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL2217471 | 1.00 | HSD11B1 (0.47) | HSD11B1ALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL2219433 | 0.94 | HSD11B1 (0.51) | HSD11B1ALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL2216745 | 0.85 | HSD11B1 (0.51) | HSD11B1ALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL2216749 | 0.85 | HSD11B1 (0.51) | HSD11B1ALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL1582322 | 0.83 | ALDH1A1 (0.46) | HSD11B1ALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL1582323 | 0.83 | ALDH1A1 (0.46) | HSD11B1ALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL2218331 | 0.83 | L3MBTL1 (0.54) | HSD11B1NPC1RAB9AL3MBTL1HPGD | |
| SCHEMBL2218337 | 0.83 | L3MBTL1 (0.54) | HSD11B1NPC1RAB9AL3MBTL1HPGD | |
| SCHEMBL2217629 | 0.81 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785452-B2 | Anti-infective compounds | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2014-07-22 | — | — | US | disclosed |
| EP-2730576-A2 | Anti-infective compounds | Institut Pasteur Korea (KR) | 2014-05-14 | — | — | EP | disclosed |
| US-20110178077-A1 | Anti-infective compounds | INSTITUT PASTEUR KOREA (KR) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178077-A1 | Anti-infective compounds | RABGGTB, ELANE, SERPINB1 | HSD11B1 3190/4885ALDH1A1 3932/4885NPC1 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.