Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23119077 | 0.98 | L3MBTL1 (0.36) | KDM4EATML3MBTL1PTGER4KMT2A | |
| SCHEMBL23119062 | 0.98 | L3MBTL1 (0.36) | KDM4EATML3MBTL1PTGER4KMT2A | |
| SCHEMBL16260429 | 0.97 | KDM4E (0.39) | KDM4EATML3MBTL1PTGER4KMT2A | |
| SCHEMBL24549690 | 0.96 | PTGER4 (0.34) | KDM4EATML3MBTL1PTGER4KMT2A | |
| SCHEMBL18868035 | 0.95 | L3MBTL1 (0.39) | KDM4EATML3MBTL1PTGER4KMT2A | |
| SCHEMBL23118760 | 0.95 | L3MBTL1 (0.39) | KDM4EATML3MBTL1PTGER4KMT2A | |
| SCHEMBL22175317 | 0.94 | KDM4E (0.39) | KDM4EATML3MBTL1PTGER4KMT2A | |
| SCHEMBL18561381 | 0.94 | L3MBTL1 (0.40) | KDM4EATML3MBTL1PTGER4KMT2A | |
| SCHEMBL16260431 | 0.94 | KDM4E (0.38) | KDM4EATML3MBTL1PTGER4KMT2A | |
| SCHEMBL26473080 | 0.94 | KDM4E (0.38) | KDM4EATML3MBTL1PTGER4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535640-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2022-12-27 | — | — | US | disclosed |
| US-20200207794-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200207794-A1 | METAL COMPLEXES | IMMT, MCU, SOD1 | KDM4E 4470/4885ATM 4048/4885L3MBTL1 3259/4885 |
| US-11535640-B2 | Metal complexes | IMMT, MCU, SOD1 | KDM4E 4470/4885ATM 4048/4885L3MBTL1 3259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.