Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KDM6B | O15054 | 1/20 | 0.30 |
| ▸ | KDM5C | P41229 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3859830 | 0.90 | FFAR3 (0.43) | ALDH1A1SMN1; SMN2FFAR3MGAMGAA | |
| SCHEMBL27560599 | 0.80 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2FFAR3CETPP2RX7 | |
| SCHEMBL17741696 | 0.80 | FFAR3 (0.31) | SMN1; SMN2FFAR3MGAMGAASI | |
| SCHEMBL3495830 | 0.79 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2FFAR3CETPP2RX7 | |
| SCHEMBL8533430 | 0.77 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2FFAR3CETPP2RX7 | |
| SCHEMBL14958857 | 0.76 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2FFAR3CETPP2RX7 | |
| SCHEMBL21238456 | 0.76 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2FFAR3CETPP2RX7 | |
| SCHEMBL11376813 | 0.76 | MGAM (0.39) | ALDH1A1SMN1; SMN2MGAMGAASI | |
| SCHEMBL12844110 | 0.76 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2CETPP2RX7RIPK1 | |
| SCHEMBL7968390 | 0.75 | FFAR3 (0.38) | ALDH1A1SMN1; SMN2FFAR3CETPP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535640-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2022-12-27 | — | — | US | disclosed |
| US-20200207794-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200207794-A1 | METAL COMPLEXES | IMMT, MCU, SOD1 | ALDH1A1 1473/4885SMN1; SMN2 4361/4885FFAR3 4529/4885 |
| US-11535640-B2 | Metal complexes | IMMT, MCU, SOD1 | ALDH1A1 1473/4885SMN1; SMN2 4361/4885FFAR3 4529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.