Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23369354 | 0.88 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL21662997 | 0.81 | POLB (0.30) | POLB | |
| SCHEMBL3236730 | 0.79 | CYP1A2 (0.37) | ALDH1A1 | |
| SCHEMBL4128790 | 0.74 | CYP1A2 (0.36) | ALDH1A1 | |
| SCHEMBL18622305 | 0.73 | CYP2D6 (0.33) | POLB | |
| SCHEMBL1381231 | 0.72 | CYP19A1 (0.36) | POLB | |
| SCHEMBL3349568 | 0.72 | MT-CO2 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL21663136 | 0.71 | POLB (0.31) | POLB | |
| SCHEMBL16496792 | 0.71 | MT-CO2 (0.32) | — | |
| SCHEMBL15385471 | 0.71 | MAPK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535640-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2022-12-27 | — | — | US | disclosed |
| EP-3658564-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2021-05-19 | — | — | EP | disclosed |
| US-20200207794-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200207794-A1 | METAL COMPLEXES | IMMT, MCU, SOD1 | ALDH1A1 1473/4885TDP1 2399/4885POLB 1166/4885 |
| US-11535640-B2 | Metal complexes | IMMT, MCU, SOD1 | ALDH1A1 1473/4885TDP1 2399/4885POLB 1166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.