SCHEMBL22178282

SCHEMBL22178282

CCN1c2ccccc2C(C)(C)c2cc(C=C3C(=O)c4cc5ccccc5cc4C3=O)sc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.38
KMT2A Q03164 7/20 0.38
MAPT P10636 7/20 0.38
MEN1 O00255 5/20 0.38
SMN1; SMN2 Q16637 5/20 0.38
NPSR1 Q6W5P4 3/20 0.38
KDM4E B2RXH2 3/20 0.38
GPR55 Q9Y2T6 2/20 0.38
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
THRB P10828 2/20 0.34
RECQL P46063 2/20 0.34
HPGD P15428 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
HTT P42858 3/20 0.33
USP2 O75604 2/20 0.33
POLB P06746 2/20 0.33
CYP1A2 P05177 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849999 0.90 KMT2A (0.38) ALDH1A1KMT2AMAPTMEN1SMN1; SMN2
SCHEMBL25851373 0.88 KMT2A (0.36) ALDH1A1KMT2AMAPTMEN1SMN1; SMN2
SCHEMBL25849711 0.86 MAPT (0.41) ALDH1A1KMT2AMAPTMEN1SMN1; SMN2
SCHEMBL24592723 0.84 KMT2A (0.34) ALDH1A1KMT2AMAPTMEN1SMN1; SMN2
SCHEMBL22177757 0.83 PGR (0.36) ALDH1A1KMT2AMAPTMEN1SMN1; SMN2
SCHEMBL22177120 0.81 MAPT (0.37) ALDH1A1KMT2AMAPTMEN1SMN1; SMN2
SCHEMBL22178285 0.79 MARK3 (0.33) ALDH1A1KMT2AMAPTMEN1SMN1; SMN2
SCHEMBL17773906 0.78 MAPT (0.32) ALDH1A1KMT2AMAPTMEN1SMN1; SMN2
SCHEMBL25849792 0.78 MAPT (0.46) ALDH1A1KMT2AMAPTMEN1SMN1; SMN2
SCHEMBL23128478 0.76 MAPT (0.42) ALDH1A1KMT2AMAPTMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11785843-B2 Photoelectric conversion element, optical sensor, and imaging element FUJIFILM CORPORATION (JP) 2023-10-10 US disclosed
US-11785843-B2 Photoelectric conversion element, optical sensor, and imaging element FUJIFILM CORPORATION (JP) 2023-10-10 US disclosed
US-20200212107-A1 PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL SENSOR, AND IMAGING ELEMENT FUJIFILM CORPORATION (JP) 2020-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11785843-B2 Photoelectric conversion element, optical sensor, and imaging element CRY1, PIN4, PPOX ALDH1A1 519/4885KMT2A 2900/4885MAPT 702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.