SCHEMBL22178285

SCHEMBL22178285

CC1(C)c2ccccc2N(C2CCCCC2)c2sc(C=C3C(=O)c4cc5ccccc5cc4C3=O)cc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MARK3 P27448 2/20 0.33
MARK4 Q96L34 1/20 0.33
MAPT P10636 3/20 0.32
KMT2A Q03164 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
USP2 O75604 1/20 0.32
POLB P06746 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 2/20 0.31
ALDH1A1 P00352 1/20 0.31
THRB P10828 1/20 0.31
HPGD P15428 1/20 0.31
RECQL P46063 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
OPRL1 P41146 3/20 0.31
OPRM1 P35372 2/20 0.31
OPRK1 P41145 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22177124 0.82 MARK3 (0.34) MARK3MARK4MAPTKMT2ASMN1; SMN2
SCHEMBL25849711 0.81 MAPT (0.41) MAPTKMT2ASMN1; SMN2MEN1NPC1
SCHEMBL22177566 0.81 OPRM1 (0.42) OPRL1OPRM1OPRK1
SCHEMBL22177496 0.81 MARK3 (0.33) MARK3MARK4MAPTKMT2ASMN1; SMN2
SCHEMBL24592723 0.80 KMT2A (0.34) MAPTKMT2ASMN1; SMN2MEN1NPC1
SCHEMBL22177757 0.79 PGR (0.36) MAPTKMT2ASMN1; SMN2MEN1NPC1
SCHEMBL22178282 0.79 ALDH1A1 (0.38) MAPTKMT2ASMN1; SMN2MEN1NPC1
SCHEMBL17773906 0.74 MAPT (0.32) MAPTKMT2ASMN1; SMN2MEN1NPC1
SCHEMBL22178287 0.74 PGR (0.34) MARK3MARK4MAPTKMT2ASMN1; SMN2
SCHEMBL25849792 0.74 MAPT (0.46) MAPTKMT2ASMN1; SMN2MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11785843-B2 Photoelectric conversion element, optical sensor, and imaging element FUJIFILM CORPORATION (JP) 2023-10-10 US disclosed
US-11785843-B2 Photoelectric conversion element, optical sensor, and imaging element FUJIFILM CORPORATION (JP) 2023-10-10 US disclosed
US-20200212107-A1 PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL SENSOR, AND IMAGING ELEMENT FUJIFILM CORPORATION (JP) 2020-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11785843-B2 Photoelectric conversion element, optical sensor, and imaging element CRY1, PIN4, PPOX MARK3 640/4885MARK4 342/4885MAPT 702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.