SCHEMBL22178283

SCHEMBL22178283

CCN1c2ccc(C=C3C(=O)c4cc5ccccc5cc4C3=O)cc2C(C)(C)c2cc(-c3c(C)cc(C)cc3C)ccc21

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.32
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 2/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
BCL2 P10415 1/20 0.31
BAX Q07812 1/20 0.31
BCL2L1 Q07817 1/20 0.31
LCK P06239 1/20 0.31
ACHE P22303 1/20 0.31
BRD4 O60885 1/20 0.30
GAA P10253 1/20 0.30
USP2 O75604 1/20 0.30
PKM P14618 1/20 0.30
DHODH Q02127 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22178288 0.90 LCK (0.38) LCK
SCHEMBL25849749 0.89 BCL2 (0.32) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL25850676 0.89 BCL2 (0.32) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL26746791 0.89 BCL2 (0.32) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL22177120 0.86 MAPT (0.37) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL22178284 0.85 APAF1 (0.33)
SCHEMBL25849753 0.83 RET (0.36) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL25165447 0.83 LCK (0.31) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL22177126 0.83 KMT2A (0.34) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL25849998 0.80 CSNK2A2 (0.40) MAPTALDH1A1KDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11785843-B2 Photoelectric conversion element, optical sensor, and imaging element FUJIFILM CORPORATION (JP) 2023-10-10 US disclosed
US-11785843-B2 Photoelectric conversion element, optical sensor, and imaging element FUJIFILM CORPORATION (JP) 2023-10-10 US disclosed
US-20230132579-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-05-04 US disclosed
US-20230132579-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-05-04 US disclosed
US-20230121151-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-04-20 US disclosed
US-20200212107-A1 PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL SENSOR, AND IMAGING ELEMENT FUJIFILM CORPORATION (JP) 2020-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11785843-B2 Photoelectric conversion element, optical sensor, and imaging element CRY1, PIN4, PPOX MAPT 702/4885ALDH1A1 519/4885KDM4E 898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.