SCHEMBL22178288

SCHEMBL22178288

CCN1c2ccc(C=C3C(=O)c4cc(Cl)c(Cl)cc4C3=O)cc2C(C)(C)c2cc(-c3c(C)cc(C)cc3C)ccc21

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LCK P06239 2/20 0.38
APAF1 O14727 1/20 0.35
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
CSNK2A1 P68400 1/20 0.31
CSNK2A3 Q8NEV1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22178283 0.90 MAPT (0.32) LCK
SCHEMBL22178284 0.90 APAF1 (0.33) APAF1
SCHEMBL25165447 0.81 LCK (0.31) LCK
SCHEMBL22177585 0.80 LCK (0.38) LCK
SCHEMBL25849749 0.79 BCL2 (0.32) LCKCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL26746791 0.78 BCL2 (0.32) LCKCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL25850676 0.78 BCL2 (0.32) LCKCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL25849998 0.78 CSNK2A2 (0.40) LCKCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL25850008 0.76 CSNK2A2 (0.38) LCKCSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL22177120 0.75 MAPT (0.37) LCKCSNK2A2CSNK2BCSNK2A1CSNK2A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11785843-B2 Photoelectric conversion element, optical sensor, and imaging element FUJIFILM CORPORATION (JP) 2023-10-10 US disclosed
US-11785843-B2 Photoelectric conversion element, optical sensor, and imaging element FUJIFILM CORPORATION (JP) 2023-10-10 US disclosed
US-20200212107-A1 PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL SENSOR, AND IMAGING ELEMENT FUJIFILM CORPORATION (JP) 2020-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11785843-B2 Photoelectric conversion element, optical sensor, and imaging element CRY1, PIN4, PPOX LCK 3861/4885APAF1 795/4885CSNK2A2 3525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.