SCHEMBL22178287

SCHEMBL22178287

CC1(C)c2ccccc2N(C2CCCCC2)c2ccc(C=C3C(=O)c4cc(F)c(F)cc4C3=O)cc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 3/20 0.34
MEN1 O00255 3/20 0.33
MAPT P10636 3/20 0.33
KMT2A Q03164 3/20 0.33
HTT P42858 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4C Q9H3R0 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
TNKS O95271 1/20 0.33
NPC1 O15118 1/20 0.33
USP2 O75604 1/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33
OPRL1 P41146 3/20 0.32
CCR1 P32246 1/20 0.32
CCR2 P41597 1/20 0.32
LCK P06239 1/20 0.32
MARK3 P27448 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22177124 0.91 MARK3 (0.34) MEN1MAPTKMT2AHTTALDH1A1
SCHEMBL22177496 0.89 MARK3 (0.33) MEN1MAPTKMT2AHTTALDH1A1
SCHEMBL22177118 0.89 LCK (0.41) MEN1MAPTKMT2AHTTALDH1A1
SCHEMBL22177497 0.86 ALDH1A1 (0.38) MEN1MAPTKMT2AHTTALDH1A1
SCHEMBL22177575 0.81 NR1H4 (0.41) MEN1MAPTKMT2AHTTALDH1A1
SCHEMBL22177565 0.80 MAPT (0.38) MEN1MAPTKMT2AHTTALDH1A1
SCHEMBL22177498 0.79 MAPT (0.39) MEN1MAPTKMT2AHTTALDH1A1
SCHEMBL22177122 0.78 OPRL1 (0.32) MEN1MAPTKMT2AHTTALDH1A1
SCHEMBL22177577 0.78 LMNA (0.33) MEN1MAPTKMT2AHTTALDH1A1
SCHEMBL26829123 0.74 NPSR1 (0.41) MEN1KMT2AHTTTNKSOPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11785843-B2 Photoelectric conversion element, optical sensor, and imaging element FUJIFILM CORPORATION (JP) 2023-10-10 US disclosed
US-11785843-B2 Photoelectric conversion element, optical sensor, and imaging element FUJIFILM CORPORATION (JP) 2023-10-10 US disclosed
US-20200212107-A1 PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL SENSOR, AND IMAGING ELEMENT FUJIFILM CORPORATION (JP) 2020-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11785843-B2 Photoelectric conversion element, optical sensor, and imaging element CRY1, PIN4, PPOX PGR 2549/4885MEN1 590/4885MAPT 702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.