Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.37 |
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | CA2 | P00918 | 6/20 | 0.37 |
| ▸ | CA9 | Q16790 | 6/20 | 0.37 |
| ▸ | CA7 | P43166 | 4/20 | 0.37 |
| ▸ | CA4 | P22748 | 3/20 | 0.37 |
| ▸ | HTR3A | P46098 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22182070 | 0.92 | HEXA (0.36) | CA12CA1CA2CA9MAPT | |
| SCHEMBL22182076 | 0.85 | ALDH1A1 (0.48) | CA12CA1CA2CA9CA7 | |
| SCHEMBL22182093 | 0.75 | SIRT1 (0.54) | CA12CA1CA2CA9MAPT | |
| SCHEMBL22181912 | 0.74 | HEXA (0.52) | MAPTHPGDALDH1A1THRBPOLB | |
| SCHEMBL22182116 | 0.73 | TP53 (0.44) | MAPTHPGDALDH1A1THRBPOLB | |
| SCHEMBL22181838 | 0.72 | HDAC3 (0.35) | HPGDALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL22182014 | 0.70 | HEXA (0.36) | MAPTPOLBMEN1KMT2A | |
| SCHEMBL22181871 | 0.69 | ALDH1A1 (0.55) | MAPTHPGDALDH1A1THRBPOLB | |
| SCHEMBL22182108 | 0.68 | USP2 (0.41) | MAPTHPGDALDH1A1POLBKDM4E | |
| SCHEMBL22181895 | 0.67 | ALDH1A1 (0.59) | MAPTHPGDALDH1A1THRBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020139291-A1 | NAPHTHALIMIDE DERIVATIVES AS ANTI-PARASITIC AGENTS FOR THE TREATMENT OF LEISHMANIASIS AS WELL AS VIRAL, BACTERIAL AND NEOPLASTIC DISEASES | ISTANBUL MEDIPOL UNIVERSITESI (TR) | 2020-07-02 | — | — | WO | disclosed |