Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4328386 | 1.00 | FTO (0.53) | FTOCA12CA9CA1KDM4E | |
| Thiophene SCHEMBL28386493 | 0.87 | FTO (0.43) | FTOCA12CA9CA1KDM4E | |
| SCHEMBL27741076 | 0.83 | ESR1 (0.52) | MEN1KMT2ASHBGCYP3A4CYP2D6 | |
| SCHEMBL276360 | 0.81 | CA12 (0.50) | FTOCA12CA9CA1KDM4E | |
| Ethoxycarbonyl Group SCHEMBL28007143 | 0.79 | CHRM2 (0.41) | FTOCA12CA9CA1KDM4E | |
| SCHEMBL7039173 | 0.76 | ACHE (0.40) | FTOCA12CA9CA1KDM4E | |
| SCHEMBL29756248 | 0.75 | DYRK1A (0.50) | CA12KDM4EHSD17B10CYP3A4CYP2D6 | |
| Benzofuran SCHEMBL7600280 | 0.74 | MMP3 (0.42) | FTOCA12CA9CA1KDM4E | |
| SCHEMBL2149910 | 0.73 | CYP2A6 (0.54) | KDM4EHSD17B10CYP3A4CYP2D6CYP2A6 | |
| SCHEMBL28384167 | 0.73 | KDM4E (0.48) | FTOCA12CA9KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 506 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119192105-A | Process for the preparation of 6-benzofuranols | 安徽昊帆生物有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-113583320-B | Crosslinkable polyolefin composition, preparation method and application thereof, crosslinked polyolefin and application thereof | 国家能源投资集团有限责任公司 | 2023-09-05 | — | — | CN | claimed |
| CN-109956919-A | Benzofuran acetamides and its application containing propyl alcohol amine structure | 沈阳药科大学 | 2019-07-02 | — | — | CN | claimed |
| WO-2016154694-A1 | N-ACYLHYDRAZONE COMPOUNDS INHIBITING HISTONE DESACETYLASE ENZYMES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHOD FOR PRODUCING SAME | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO-UFRJ (BR) | 2016-10-06 | — | — | WO | claimed |
| US-5730962-A | Depigmenting cosmetic or dermatologic composition containing a benzofuran derivative and its use in depigmentating skin | L'OREAL (FR) | 1998-03-24 | — | — | US | claimed |
| WO-1996012489-A1 | BICYCLIC NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-05-02 | — | — | WO | claimed |
| WO-1996012488-A1 | BICYCLIC BRADYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-05-02 | — | — | WO | claimed |
| EP-0524108-B1 | Use of derivatives of benzofurane as depigmentation agents in cosmetic or dermatological compositions | OREAL (FR) | 1995-06-07 | — | — | EP | claimed |
| JP-2225542-A | — | — | None | — | — | JP | disclosed |
| JP-5221847-A | — | — | None | — | — | JP | disclosed |
| JP-3261705-A | — | — | None | — | — | JP | disclosed |
| JP-53078248-A | — | — | None | — | — | JP | disclosed |
| JP-53114852-A | — | — | None | — | — | JP | disclosed |
| JP-59044376-A | — | — | None | — | — | JP | disclosed |
| JP-S5944376-A | PREPARATION OF 6-HYDROXYCOUMARONE DERIVATIVE | NIPPON PETROCHEM CO LTD | 1984-03-12 | — | — | JP | disclosed |
| US-4178184-A | DIHYDROXYDIPHENYL COMPOUND AND FUSED OXYGEN HETEROCYCLE | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1979-12-11 | — | — | US | disclosed |
| JP-S5420056-A | THERMOPLASTIC POLYMER COMPOSITION | MITSUI PETROCHEM IND LTD | 1979-02-15 | — | — | JP | disclosed |
| JP-S53114852-A | POLYOLEFIN COMPOSITION | MITSUI PETROCHEM IND LTD | 1978-10-06 | — | — | JP | disclosed |
| JP-S5378248-A | METHOD OF PREVENTING YELLOWING OF POLYOLEFIN COMPOSITION | MITSUI PETROCHEM IND LTD | 1978-07-11 | — | — | JP | disclosed |
| JP-S05378248-A | — | — | 0001-01-01 | — | — | JP | disclosed |