Sugi Predict

Sugi Predict / Compounds / SCHEMBL276360

SCHEMBL276360

SCHEMBL276360

Oc1ccc2occc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 2/20 0.50
▸ CA9 Q16790 2/20 0.50
▸ CYP2A6 P11509 2/20 0.50
▸ MCL1 Q07820 1/20 0.50
▸ CA1 P00915 1/20 0.50
▸ FTO Q9C0B1 1/20 0.48
▸ DYRK1A Q13627 4/20 0.47
▸ CDK9 P50750 1/20 0.46
▸ EPM2A O95278 1/20 0.44
▸ PTPRC P08575 1/20 0.44
▸ PTPN6 P29350 1/20 0.44
▸ CDC14A Q9UNH5 1/20 0.44
▸ PTPN22 Q9Y2R2 1/20 0.44
▸ FLT3 P36888 1/20 0.44
▸ ESR1 P03372 1/20 0.44
▸ ESR2 Q92731 1/20 0.44
▸ CTNNB1 P35222 2/20 0.43
▸ WNT3A P56704 2/20 0.43
▸ HTR1B P28222 2/20 0.42
▸ KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL28380622 0.90 CTNNB1 (0.49) CA12CA9CYP2A6MCL1CA1
SCHEMBL28135391 0.83 DYRK1A (0.65) CA12DYRK1ACDK9ESR1ESR2
SCHEMBL14157440 0.81 ESR1 (0.68) CA12CA9MCL1CA1DYRK1A
SCHEMBL221829 0.81 FTO (0.53) CA12CA9CYP2A6MCL1CA1
SCHEMBL4328386 0.81 FTO (0.53) CA12CA9CYP2A6MCL1CA1
Ethoxycarbonyl Group SCHEMBL27648948 0.79 CYP2A6 (0.45) CA12CA9CYP2A6MCL1FTO
SCHEMBL30819828 0.77 FTO (0.50) CA12CA9CYP2A6MCL1CA1
SCHEMBL8133413 0.77 FTO (0.50) CA12CA9CYP2A6MCL1CA1
SCHEMBL31280683 0.76 ESR1 (0.53) CYP2A6DYRK1ACDK9EPM2APTPRC
Benzofuran SCHEMBL7600280 0.74 MMP3 (0.42) CA12CA9MCL1CA1FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 550 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775241-A 5-Hydroxy benzofuran derivative and preparation method thereof 华东理工大学 2025-04-08 — — CN claimed
CN-113583320-B Crosslinkable polyolefin composition, preparation method and application thereof, crosslinked polyolefin and application thereof 国家能源投资集团有限责任公司 2023-09-05 — — CN claimed
CN-112225713-B Synthesis process of 5-hydroxybenzofuran compound 华东理工大学 2023-02-28 — — CN claimed
CN-113122062-A Quantum dot ink and preparation method of quantum dot film TCL集团股份有限公司 2021-07-16 — — CN claimed
CN-112225713-A Synthesis process of 5-hydroxybenzofuran compound 华东理工大学 2021-01-15 — — CN claimed
CN-104478862-B New benzofurans suitable as precursors to compounds that are useful for imaging amyloid deposits 阿斯利康(瑞典)有限公司 2017-05-24 — — CN claimed
WO-2016154694-A1 N-ACYLHYDRAZONE COMPOUNDS INHIBITING HISTONE DESACETYLASE ENZYMES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHOD FOR PRODUCING SAME UNIVERSIDADE FEDERAL DO RIO DE JANEIRO-UFRJ (BR) 2016-10-06 — — WO claimed
US-9309267-B2 Compounds suitable as precursors to compounds that are useful for imaging amyloid deposits ASTRAZENECA AB (SE) 2016-04-12 — — US claimed
US-20110065715-A1 Nogo Receptor Binding Small Molecules to Promote Axonal Growth YALE UNIVERSITY (US) 2011-03-17 — — US claimed
EP-2220499-A2 NOGO RECEPTOR BINDING SMALL MOLECULES TO PROMOTE AXONAL GROWTH Yale University (US) 2010-08-25 — — EP claimed
WO-2009073141-A2 NOGO RECEPTOR BINDING SMALL MOLECULES TO PROMOTE AXONAL GROWTH STRITTMATTER STEPHEN M (US) 2009-06-11 — — WO claimed
US-5730962-A Depigmenting cosmetic or dermatologic composition containing a benzofuran derivative and its use in depigmentating skin L'OREAL (FR) 1998-03-24 — — US claimed
EP-0524108-B1 Use of derivatives of benzofurane as depigmentation agents in cosmetic or dermatological compositions OREAL (FR) 1995-06-07 — — EP claimed
US-12509460-B2 Methods and compositions for modulating splicing SKYHAWK THERAPEUTICS, INC. (US) 2025-12-30 — — US disclosed
US-20250340547-A1 NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) 2025-11-06 — — US disclosed
CN-119775241-A 5-Hydroxy benzofuran derivative and preparation method thereof 华东理工大学 2025-04-08 — — CN disclosed
US-4120871-A HERBICIDES, PLANT GROWTH REGULATORS FISONS LIMITED (GB) 1978-10-17 — — US disclosed
US-3983141-A Derivatives of 5-hydroxy-6-diloweralkylaminomethyl-benzofurans GRINEV ALEXEI NIKOLAEVICH 1976-09-28 — — US disclosed
US-3983141-A Derivatives of 5-hydroxy-6-diloweralkylaminomethyl-benzofurans GRINEV ALEXEI NIKOLAEVICH 1976-09-28 — — US disclosed
US-3946048-A HERBICIDES BASF AKTIENGESELLSCHAFT (DT) 1976-03-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509460-B2 Methods and compositions for modulating splicing SF3B1, RTCB, RBM17 CA12 4814/4885CA9 4816/4885CYP2A6 2749/4885
US-20250340547-A1 NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN MAPT, FABP7, HTT CA12 3607/4885CA9 3723/4885CYP2A6 3887/4885
US-20110065715-A1 Nogo Receptor Binding Small Molecules to Promote Axonal Growth NGFR, GAP43, BDNF CA12 4805/4885CA9 4869/4885CYP2A6 4175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.