SCHEMBL22186706

SCHEMBL22186706

c1ccc(-c2cccc(-n3c4cc5c(cc4c4c6ccccc6ccc43)c3ccccc3n5-c3ccc4ccccc4c3)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.39
KDM4E B2RXH2 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
F2 P00734 1/20 0.33
F10 P00742 1/20 0.33
PRSS1 P07477 1/20 0.33
TSPO P30536 2/20 0.32
HPGD P15428 1/20 0.32
PTGES O14684 1/20 0.31
PDE10A Q9Y233 1/20 0.31
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31
TUBA3C P0DPH7 1/20 0.31
TUBA1B P68363 1/20 0.31
TUBA4A P68366 1/20 0.31
TUBB4B P68371 1/20 0.31
TUBB3 Q13509 1/20 0.31
TUBB2A Q13885 1/20 0.31
TUBB8 Q3ZCM7 1/20 0.31
TUBA3E Q6PEY2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22186517 1.00 ATM (0.39) ATMKDM4EL3MBTL1F2F10
SCHEMBL22186213 0.94 L3MBTL1 (0.45) ATMKDM4EL3MBTL1TSPOPTGES
SCHEMBL22186437 0.94 L3MBTL1 (0.45) ATMKDM4EL3MBTL1TSPOPTGES
SCHEMBL22186218 0.93 L3MBTL1 (0.42) ATMKDM4EL3MBTL1F2F10
SCHEMBL22868920 0.93 L3MBTL1 (0.44) ATMKDM4EL3MBTL1TSPOPTGES
SCHEMBL22483476 0.93 KDM4E (0.41) ATMKDM4EL3MBTL1F2F10
SCHEMBL19037008 0.92 ATM (0.44) ATMKDM4EL3MBTL1TSPOPTGES
SCHEMBL24004212 0.92 KDM4E (0.47) ATMKDM4EL3MBTL1F2F10
SCHEMBL17989800 0.92 KDM4E (0.47) ATMKDM4EL3MBTL1F2F10
SCHEMBL23233770 0.92 ATM (0.46) ATMKDM4EL3MBTL1F2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3972003-A2 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME Rohm And Haas Electronic Materials Korea Ltd. (KR) 2022-03-23 EP disclosed
US-20210028373-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-01-28 US disclosed
US-20200212310-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2020-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210028373-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERT, TELO2, LIMS1 ATM 2257/4885KDM4E 3066/4885L3MBTL1 46/4885
US-20200212310-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME SOD1, TRPA1, LPO ATM 3092/4885KDM4E 3013/4885L3MBTL1 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.