SCHEMBL22187705

SCHEMBL22187705

Cc1cc(C2(c3ccc(O)c(C)c3)c3ccc(-c4ccccc4)cc3-c3cc(-c4ccccc4)ccc32)ccc1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 6/20 0.68
ESR1 P03372 4/20 0.68
MEN1 O00255 3/20 0.48
LMNA P02545 3/20 0.48
MAPT P10636 3/20 0.48
KMT2A Q03164 3/20 0.48
XBP1 P17861 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
HSD17B1 P14061 4/20 0.47
HSD17B2 P37059 4/20 0.47
POLB P06746 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ALOX5 P09917 1/20 0.43
KDM4E B2RXH2 2/20 0.40
USP2 O75604 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HSP90AA1 P07900 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13849105 0.88 ESR2 (0.68) ESR2ESR1MEN1LMNAMAPT
SCHEMBL13849021 0.88 ESR2 (0.68) ESR2ESR1MEN1LMNAMAPT
SCHEMBL27113678 0.87 ESR2 (0.76) ESR2ESR1MEN1LMNAMAPT
SCHEMBL22187630 0.87 ESR2 (0.62) ESR2ESR1MEN1LMNAMAPT
SCHEMBL22187652 0.85 HSD17B1 (0.48) ESR2ESR1MEN1LMNAMAPT
SCHEMBL22187742 0.81 ESR1 (0.62) ESR2ESR1MEN1LMNAMAPT
SCHEMBL29450641 0.81 ESR1 (1.00) ESR2ESR1MEN1LMNAMAPT
SCHEMBL29358768 0.81 ESR1 (1.00) ESR2ESR1MEN1LMNAMAPT
SCHEMBL70957 0.81 ESR1 (1.00) ESR2ESR1MEN1LMNAMAPT
SCHEMBL18386002 0.80 ESR1 (0.90) ESR2ESR1MEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12441880-B2 Poly(ester)carbonate and method for producing poly(ester)carbonate TEIJIN LIMITED (JP) 2025-10-14 US disclosed
EP-3733734-B1 POLY(ESTER)CARBONATE AND METHOD FOR PRODUCING POLY(ESTER)CARBONATE TEIJIN LTD (JP) 2024-03-06 EP disclosed
US-20230051676-A1 POLYCARBONATE AND METHOD FOR PRODUCING POLYCARBONATE TEIJIN LIMITED (JP) 2023-02-16 US disclosed
US-11505698-B2 Polyester carbonate and method for producing polyester carbonate TEIJIN LIMITED (JP) 2022-11-22 US disclosed
US-11339249-B2 Compound having fluorene skeleton, and method for manufacturing same TEIJIN LIMITED (JP) 2022-05-24 US disclosed
US-11261294-B2 Thermoplastic resin and optical member TEIJIN LIMITED (JP) 2022-03-01 US disclosed
US-20210371650-A1 POLY(ESTER)CARBONATE AND METHOD FOR PRODUCING POLY(ESTER)CARBONATE TEIJIN LIMITED (JP) 2021-12-02 US disclosed
US-20210147621-A1 THERMOPLASTIC RESIN AND OPTICAL MEMBER TEIJIN LIMITED (JP) 2021-05-20 US disclosed
EP-3747856-A1 COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME Teijin Limited (JP) 2020-12-09 EP disclosed
US-20200354517-A1 COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME TEIJIN LIMITED (JP) 2020-11-12 US disclosed
EP-3733734-A1 POLY(ESTER)CARBONATE AND METHOD FOR PRODUCING POLY(ESTER)CARBONATE Teijin Limited (JP) 2020-11-04 EP disclosed
EP-3677614-A1 THERMOPLASTIC RESIN AND OPTICAL MEMBER Teijin Limited (JP) 2020-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354517-A1 COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME RFT1, AFF1, RER1 ESR2 1835/4885ESR1 2497/4885MEN1 99/4885
US-11339249-B2 Compound having fluorene skeleton, and method for manufacturing same RFT1, AFF1, RER1 ESR2 1835/4885ESR1 2497/4885MEN1 99/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.