Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | NT5E | P21589 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Coumarin SCHEMBL28998357 | 0.91 | CA12 (0.61) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL3692740 | 0.82 | HPGD (0.51) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL145996 | 0.81 | SMN1; SMN2 (0.51) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL5188804 | 0.79 | KDM4E (0.49) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| Camphor SCHEMBL27715973 | 0.78 | ALDH1A1 (0.50) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL13768988 | 0.77 | ALDH1A1 (0.52) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL28682649 | 0.76 | MAOB (0.57) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL28880946 | 0.76 | SMN1; SMN2 (0.53) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL28996736 | 0.76 | MAOB (0.54) | HPGDSMN1; SMN2TYRDAOAKR1B1 | |
| SCHEMBL30241252 | 0.76 | MAOB (0.54) | HPGDSMN1; SMN2TYRDAOAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859223-B1 | Compositions and methods for imaging beta-secretase activity in living cells and organisms | DUKE UNIVERSITY (US) | 2014-10-14 | — | — | US | claimed |
| US-8771644-B2 | Imaging probes | SANOFI (FR) | 2014-07-08 | — | — | US | claimed |
| CN-101652149-B | Imaging probes | SANOFI AVENTIS FR | 2012-11-14 | — | — | CN | claimed |
| EP-2117605-B1 | IMAGING PROBES | SANOFI SA (FR) | 2012-09-26 | — | — | EP | claimed |
| US-20110059018-A1 | COVALENTLY BINDING IMAGING PROBES | SANOFI-AVENTIS (FR) | 2011-03-10 | — | — | US | claimed |
| EP-2262783-A2 | COVALENTLY BINDING IMAGING PROBES | Sanofi-Aventis (FR) | 2010-12-22 | — | — | EP | claimed |
| US-20100303728-A1 | CASPASE IMAGING PROBES | SANOFI-AVENTIS (FR) | 2010-12-02 | — | — | US | claimed |
| US-20100189658-A1 | Imaging probes | SANOFI-AVENTIS (FR) | 2010-07-29 | — | — | US | claimed |
| US-20100112598-A1 | Novel Assay for Inositol Phosphorylceramide Synthase Activity | AUREOGEN BIOSCIENCES, INC. (US) | 2010-05-06 | — | — | US | claimed |
| CN-101652149-A | imaging probes | SANOFI AVENTIS FR | 2010-02-17 | — | — | CN | claimed |
| US-7659088-B2 | Assay for inositol phosphorylceramide synthase activity | AUREOGEN BIOSCIENCES, INC. (US) | 2010-02-09 | — | — | US | claimed |
| EP-2117605-A2 | IMAGING PROBES | Sanofi-Aventis (FR) | 2009-11-18 | — | — | EP | claimed |
| WO-2009103432-A2 | COVALENTLY BINDING IMAGING PROBES | SANOFI-AVENTIS (FR) | 2009-08-27 | — | — | WO | claimed |
| WO-2008104271-A2 | IMAGING PROBES | SANOFI-AVENTIS (FR) | 2008-09-04 | — | — | WO | claimed |
| US-20070269844-A1 | Novel assay for inositol phosphorylceramide synthase activity | AUREOGEN, INC. | 2007-11-22 | — | — | US | claimed |
| US-20260066042-A1 | METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS | OPENTRONS LABWORKS INC (US) | 2026-03-05 | — | — | US | disclosed |
| EP-4662244-A1 | ANTI-MESOTHELIN NANOBODIES, CONSTRUCTS AND CONJUGATES | Université d'Aix Marseille (FR) | 2025-12-17 | — | — | EP | disclosed |
| CN-1275904-A | Hair care compositions comprising optical brighteners which alter hair colors | PROCTER & GAMBLE (US) | 2000-12-06 | — | — | CN | disclosed |
| CN-1275902-A | Hair care compositions comprising optical brighteners and non-volatile solvents | PROCTER & GAMBLE (US) | 2000-12-06 | — | — | CN | disclosed |
| CN-1275903-A | Hair care compositions comprising optical brighteners which provide UV protection | PROCTER & GAMBLE (US) | 2000-12-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100189658-A1 | Imaging probes | CTSV, CTSL, CTSB | HPGD 2698/4885SMN1; SMN2 2014/4885TYR 2404/4885 |
| US-20110059018-A1 | COVALENTLY BINDING IMAGING PROBES | CTSV, CTSL, CTSE | HPGD 3298/4885SMN1; SMN2 2684/4885TYR 3226/4885 |
| US-20260066042-A1 | METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS | POLRMT, POLL, SARS1 | HPGD 4853/4885SMN1; SMN2 3068/4885TYR 4653/4885 |
| US-20100303728-A1 | CASPASE IMAGING PROBES | CASP1, CASP2, CASP3 | HPGD 2422/4885SMN1; SMN2 956/4885TYR 4535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.