Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.55 |
| ▸ | ALB | P02768 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTRA2 | O43464 | 4/20 | 0.46 |
| ▸ | HTRA1 | Q92743 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22189249 | 1.00 | FOLH1 (0.55) | FOLH1ALBCA9USP2L3MBTL1 | |
| SCHEMBL13077419 | 0.86 | ALB (0.61) | FOLH1ALBCA9USP2L3MBTL1 | |
| SCHEMBL20661627 | 0.86 | ALB (0.56) | FOLH1ALBCA9USP2L3MBTL1 | |
| SCHEMBL22189221 | 0.85 | HTRA2 (0.60) | FOLH1ALBHTRA2HTRA1SLC5A2 | |
| SCHEMBL22189219 | 0.85 | HTRA2 (0.60) | FOLH1ALBHTRA2HTRA1SLC5A2 | |
| SCHEMBL15130552 | 0.81 | USP2 (0.62) | FOLH1ALBCA9USP2L3MBTL1 | |
| SCHEMBL13287065 | 0.80 | USP2 (0.60) | FOLH1ALBCA9USP2L3MBTL1 | |
| SCHEMBL21730313 | 0.80 | ALB (0.59) | FOLH1ALBCA9USP2L3MBTL1 | |
| SCHEMBL16295184 | 0.79 | FOLH1 (0.68) | FOLH1ALBCA9USP2L3MBTL1 | |
| SCHEMBL19449073 | 0.79 | FOLH1 (0.63) | FOLH1ALBCA9USP2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11219697-B2 | Osteoadsorptive fluorogenic substrate of cathepsin k for imaging osteoclast activity and migration | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-01-11 | — | — | US | disclosed |
| US-20200215205-A1 | AN OSTEOADSORPTIVE FLUOROGENIC SUBSTRATE OF CATHEPSIN K FOR IMAGING OSTEOCLAST ACTIVITY AND MIGRATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11219697-B2 | Osteoadsorptive fluorogenic substrate of cathepsin k for imaging osteoclast activity and migration | CTSS, CTSK, CTSF | FOLH1 496/4885ALB 4711/4885CA9 718/4885 |
| US-20200215205-A1 | AN OSTEOADSORPTIVE FLUOROGENIC SUBSTRATE OF CATHEPSIN K FOR IMAGING OSTEOCLAST ACTIVITY AND MIGRATION | CTSS, CTSK, CTSF | FOLH1 451/4885ALB 4665/4885CA9 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.