SCHEMBL221911

SCHEMBL221911

CCCCc1ccc(N(c2ccc(C(C)C)cc2)c2ccc(C3C=CC(c4ccccc4)(N(c4ccc(CCCC)cc4)c4ccc(C(C)C)cc4)C=C3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 1/20 0.35
HTR2A P28223 1/20 0.34
UCHL3 P15374 2/20 0.33
BCHE P06276 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CNR1 P21554 2/20 0.31
CNR2 P34972 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL223517 0.89 CNR2 (0.38) OPRL1BCHECNR2
SCHEMBL221878 0.83 CNR2 (0.31) CNR2
SCHEMBL223877 0.81 HSD11B1 (0.31) OPRL1
SCHEMBL2268708 0.80 CNR2 (0.33) CNR2
SCHEMBL4213708 0.78 ALDH1A1 (0.35)
SCHEMBL253618 0.78 CNR2 (0.32) CNR2
SCHEMBL1323554 0.76
SCHEMBL19125480 0.74 KDM4E (0.32)
SCHEMBL221912 0.71 UCHL3 (0.35) OPRL1HTR2AUCHL3
SCHEMBL8862830 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3309618-A1 POLYCARBONATE CONTAINING PHOTOCONDUCTORS Xerox Corporation (US) 2018-04-18 EP claimed
US-9851647-B1 Polycarbonate containing photoconductors XEROX CORPORATION (US) 2017-12-26 US claimed
US-20150261105-A1 BIPHENYL POLYCARBONATE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2015-09-17 US claimed
US-9128392-B2 Polyarylatecarbonate containing photoconductors XEROX CORPORATION (US) 2015-09-08 US claimed
US-9069268-B2 Polyarylatecarbonate fluoropolymer containing photoconductors XEROX CORPORATION (US) 2015-06-30 US claimed
US-20150147690-A1 POLYARYLATECARBONATE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2015-05-28 US claimed
US-20150079511-A1 POLYARYLATECARBONATE FLUOROPOLYMER CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2015-03-19 US claimed
US-20140356772-A1 TERPENE POLYCARBONATE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2014-12-04 US claimed
US-8815481-B2 Imaging member with fluorosulfonamide-containing overcoat layer XEROX CORPORATION (US) 2014-08-26 US claimed
US-8785091-B1 Polyarylatecarbonate containing photoconductors XEROX CORPORATION (US) 2014-07-22 US claimed
US-7981578-B2 Additive containing photoconductors XEROX CORPORATION (US) 2011-07-19 US claimed
US-7981579-B2 Thiadiazole containing photoconductors XEROX CORPORATION (US) 2011-07-19 US claimed
US-7972756-B2 Ketal containing photoconductors XEROX CORPORATION (US) 2011-07-05 US claimed
US-7968262-B2 Bis(enylaryl)arylamine containing photoconductors XEROX CORPORATION (US) 2011-06-28 US claimed
US-7968263-B2 Amine phosphate containing photogenerating layer photoconductors XEROX CORPORATION (US) 2011-06-28 US claimed
US-20110151365-A1 POLYALKYLENE GLYCOL BENZOATE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2011-06-23 US claimed
US-7960079-B2 Phenazine containing photoconductors XEROX CORPORATION (US) 2011-06-14 US claimed
US-7960080-B2 Oxadiazole containing photoconductors XEROX CORPORATION (US) 2011-06-14 US claimed
US-7951514-B2 Polymer anticurl backside coating (ACBC) photoconductors XEROX CORPORATION (US) 2011-05-31 US claimed
US-7932006-B2 Photoconductors XEROX CORPORATION (US) 2011-04-26 US claimed