Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 6/20 | 0.46 |
| ▸ | CA1 | P00915 | 6/20 | 0.46 |
| ▸ | CA2 | P00918 | 6/20 | 0.46 |
| ▸ | CA9 | Q16790 | 6/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21747691 | 0.98 | RAD51 (0.54) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL29498238 | 0.98 | RAD51 (0.54) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL8410072 | 0.98 | RAD51 (0.54) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL1169584 | 0.91 | RAD51 (0.60) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL893765 | 0.91 | RAD51 (0.60) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL30532269 | 0.91 | RAD51 (0.60) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL29737199 | 0.91 | RAD51 (0.60) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL2221675 | 0.91 | RAD51 (0.46) | RAD51CA12CA1CA2CA9 | |
| Potassium Ion SCHEMBL2204422 | 0.90 | RAD51 (0.56) | RAD51CA12CA1CA2CA9 | |
| Potassium Ion SCHEMBL2202992 | 0.88 | CA12 (0.56) | RAD51CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2722190-A1 | Optimized undercoat for thermal recording material | Ricoh Industrie France SAS (FR) | 2014-04-23 | — | — | EP | disclosed |
| US-8546300-B2 | Thermosensitive recording material and image recording method | RICOH COMPANY, LTD. (JP) | 2013-10-01 | — | — | US | disclosed |
| US-20110177941-A1 | THERMOSENSITIVE RECORDING MATERIAL AND IMAGE RECORDING METHOD | RICOH COMPANY, LTD. (JP) | 2011-07-21 | — | — | US | disclosed |