Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 4/20 | 0.46 |
| ▸ | CA1 known ✓ | P00915 | 4/20 | 0.46 |
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.46 |
| ▸ | P2RY4 known ✓ | P51582 | 3/20 | 0.42 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.42 |
| ▸ | P2RY12 known ✓ | Q9H244 | 3/20 | 0.42 |
| ▸ | P2RY2 known ✓ | P41231 | 2/20 | 0.42 |
| ▸ | P2RY6 known ✓ | Q15077 | 2/20 | 0.42 |
| ▸ | RAD51 | Q06609 | 8/20 | 0.60 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30532269 | 1.00 | RAD51 (0.60) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL1169584 | 1.00 | RAD51 (0.60) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL29737199 | 1.00 | RAD51 (0.60) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL4821260 | 0.95 | RAD51 (0.55) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL4821301 | 0.95 | RAD51 (0.55) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL8410050 | 0.95 | RAD51 (0.55) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL8410035 | 0.95 | RAD51 (0.55) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL8012728 | 0.94 | RAD51 (0.54) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL4435900 | 0.94 | RAD51 (0.54) | RAD51CA12CA1CA2CA9 | |
| SCHEMBL11879420 | 0.94 | CA12 (0.56) | RAD51CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11015153-B2 | Unitary laundry detergent article | THE PROCTER & GAMBLE COMPANY (US) | 2021-05-25 | — | — | US | claimed |
| EP-1555009-B1 | Skin make-up composition | OREAL (FR) | 2010-07-14 | — | — | EP | claimed |
| WO-2010065917-A1 | METHODS OF TREATING NEUROLOGICAL DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-06-10 | — | — | WO | claimed |
| US-20090218544-A1 | BLEACHING COMPOSITION COMPRISING AN ALKOXYLATED BENZOIC ACID | THE PROCTER & GAMBLE COMPANY (US) | 2009-09-03 | — | — | US | claimed |
| EP-1462564-B1 | Bleaching composition comprising trimethoxy benzoic acid or a salt thereof | PROCTER & GAMBLE (US) | 2009-01-21 | — | — | EP | claimed |
| US-20080261855-A1 | Bleaching composition comprising an alkoxylated benzoic acid | BRIATORE ANDREA | 2008-10-23 | — | — | US | claimed |
| US-20080184495-A1 | Dye composition comprising a reactive silicone and a fluorescent dye, and dyeing process using the composition | L'OREAL S.A. (FR) | 2008-08-07 | — | — | US | claimed |
| EP-1614742-B1 | Bleaching composition comprising a cyclic hindered amine | PROCTER & GAMBLE (US) | 2007-12-05 | — | — | EP | claimed |
| US-20070266502-A1 | Bleaching composition comprising a cyclic hindered amine | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-22 | — | — | US | claimed |
| US-7261744-B2 | Method for dyeing or coloring human keratin materials with lightening effect using a composition comprising at least one fluorescent compound and at least one optical brightener | L'OREAL S.A. (FR) | 2007-08-28 | — | — | US | claimed |
| US-20040241115-A1 | Nail varnish composition comprising fibers covered with at least one fluorescent whitening agent | L'OREAL S.A. (FR) | 2004-12-02 | — | — | US | claimed |
| EP-0962224-B1 | Optical azurants as skin bleaching agent | OREAL (FR) | 2004-11-03 | — | — | EP | claimed |
| WO-2004088028-A1 | BLEACHING COMPOSITION COMPRISING AN ALKOXYLATED BENZOIC ACID | THE PROCTER & GAMBLE COMPANY (US) | 2004-10-14 | — | — | WO | claimed |
| US-20040192571-A1 | Bleaching composition comprising an alkoxylated benzoic acid | THE PROCTER & GAMBLE COMPANY | 2004-09-30 | — | — | US | claimed |
| EP-1462564-A1 | Bleaching composition comprising trimethoxy benzoic acid or a salt thereof | THE PROCTER & GAMBLE COMPANY (US) | 2004-09-29 | — | — | EP | claimed |
| US-6488917-B2 | FOR BLEACHING SKIN | L'OREAL (FR) | 2002-12-03 | — | — | US | claimed |
| US-20010010812-A1 | Optical brighteners as bleaching agents | L'OREAL (FR) | 2001-08-02 | — | — | US | claimed |
| US-6203781-B1 | APPLYING COSMETIC SODIUM 4,4*BIS(4,6-DIANILINO-1,3,5-TRIAZIN-2-YL)AMINO)STILBENE-2,2*-D ISULFONATE AND 2,5-THIOPHENEDIYLBIS(5-TERT-BUTYL-1,3-BENZOXAZOLE | L'OREAL (FR) | 2001-03-20 | — | — | US | claimed |
| US-4005026-A | Detergent compositions containing novel crystalline forms of optical brighteners | STERLING DRUG INC. (US) | 1977-01-25 | — | — | US | claimed |
| US-3951960-A | BIS-TRIAZINYLAMINOSTILBENE | STERLING DRUG INC. (US) | 1976-04-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080184495-A1 | Dye composition comprising a reactive silicone and a fluorescent dye, and dyeing process using the composition | KRT18, VIM, CD44 | CA12 1362/4885CA1 1828/4885CA2 2651/4885 |
| US-20010010812-A1 | Optical brighteners as bleaching agents | GLA, CUTA, LPO | CA12 3221/4885CA1 4689/4885CA2 1917/4885 |
| US-20040241115-A1 | Nail varnish composition comprising fibers covered with at least one fluorescent whitening agent | POLR1C, NACA, DPM1 | CA12 4146/4885CA1 4685/4885CA2 3963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.