Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 4/20 | 0.36 |
| ▸ | NOS3 | P29474 | 3/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624352 | 0.86 | KDM4E (0.45) | ALDH1A1TSHRCA1CA2CA9 | |
| SCHEMBL24629872 | 0.82 | CA1 (0.50) | ALDH1A1TSHRCA1CA2CA9 | |
| SCHEMBL404738 | 0.82 | CA1 (0.48) | ALDH1A1TSHRCA1CA2CA9 | |
| SCHEMBL20670572 | 0.82 | CA1 (0.48) | ALDH1A1TSHRCA1CA2CA9 | |
| SCHEMBL22450147 | 0.78 | ALDH1A1 (0.35) | ALDH1A1TSHRCA1CA2CA9 | |
| SCHEMBL31145750 | 0.78 | NOS3 (0.36) | ALDH1A1TSHRCA1CA2CA9 | |
| SCHEMBL20670581 | 0.78 | XDH (0.53) | ALDH1A1TSHRCA1CA2CA9 | |
| SCHEMBL12528368 | 0.75 | KDM4E (0.66) | KDM4ETDP1LMNA | |
| SCHEMBL20220905 | 0.75 | ALDH1A1 (0.41) | ALDH1A1TSHRCA1KDM4ETDP1 | |
| SCHEMBL3012755 | 0.73 | GPR35 (0.52) | ALDH1A1TSHRKDM4ETDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132480-A1 | INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE | TRI-INSTITUTIONAL THERAPEUTICS DISCOVERY INSTITUTE, INC. | 2024-04-25 | — | — | US | disclosed |
| US-11535637-B2 | Compound and organic light emitting element comprising same | LG CHEM, LTD. (KR) | 2022-12-27 | — | — | US | disclosed |
| WO-2022150574-A1 | INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE | CORNELL UNIVERSITY (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2022150574-A1 | INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE | CORNELL UNIVERSITY (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2021129724-A1 | ARYLAMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | 陕西莱特光电材料股份有限公司 | 2021-07-01 | — | — | WO | disclosed |
| US-20200216475-A1 | COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2020-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132480-A1 | INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE | DLD, GCDH, DLAT | ALDH1A1 188/4885TSHR 2338/4885CA1 3932/4885 |
| US-11535637-B2 | Compound and organic light emitting element comprising same | NR2E3, NR4A2, NR2C2 | ALDH1A1 1206/4885TSHR 1677/4885CA1 1232/4885 |
| US-20200216475-A1 | COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | NR2E3, NR4A2, NR4A1 | ALDH1A1 1241/4885TSHR 603/4885CA1 1495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.