Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3667152 | 0.79 | SLC6A2 (0.49) | SLC6A2SLC6A3KMT2ATDP1ALDH1A1 | |
| SCHEMBL6559170 | 0.77 | PPARA (0.52) | TACR1CTSBCTSL | |
| SCHEMBL6559177 | 0.77 | PPARA (0.52) | TACR1CTSBCTSL | |
| SCHEMBL24194300 | 0.75 | KYNU (0.58) | TACR1ALDH1A1CTSBCTSL | |
| SCHEMBL20804450 | 0.74 | FOLH1 (0.49) | SLC6A2SLC6A3KMT2ATDP1CA1 | |
| SCHEMBL27568996 | 0.73 | ALDH1A1 (0.46) | SLC6A2SLC6A3KMT2ATDP1TACR1 | |
| SCHEMBL10885963 | 0.73 | EPHX1 (0.53) | KMT2ATACR1ITGA4ITGB7ALDH1A1 | |
| SCHEMBL27793253 | 0.72 | LTA4H (0.48) | CTSL | |
| SCHEMBL8044508 | 0.71 | CTRB1 (0.50) | SLC6A2SLC6A3KMT2ATDP1TACR1 | |
| SCHEMBL23011779 | 0.71 | ALDH1A1 (0.51) | SLC6A2SLC6A3KMT2ATDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141155-A1 | PANTOTHENAMIDE ANALOGUES | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2020-07-09 | — | — | WO | disclosed |