SCHEMBL22200027

SCHEMBL22200027

c1ccc2c(-c3ccc(-c4nc(-n5c6ccccc6c6c7ccccc7c7c8ccccc8oc7c65)nc5c4ccc4ccccc45)cc3)cccc2c1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ENPP3 O14638 1/20 0.31
ENPP1 P22413 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18132444 0.93 PRKDC (0.31)
SCHEMBL22200008 0.91 MAPT (0.33) TDP1L3MBTL1
SCHEMBL18132431 0.91 MAPT (0.34) TDP1L3MBTL1
SCHEMBL22199873 0.89 ALDH1A1 (0.36) TDP1L3MBTL1ENPP3ENPP1
SCHEMBL19986143 0.86 MEN1 (0.32) TDP1L3MBTL1
SCHEMBL19986142 0.85 MAPT (0.33) TDP1L3MBTL1
SCHEMBL22199810 0.85 ENPP3 (0.34) TDP1L3MBTL1ENPP3ENPP1
SCHEMBL24495873 0.84 PRKDC (0.31)
SCHEMBL18132466 0.84 PRKDC (0.31)
SCHEMBL24171787 0.84 MEN1 (0.32) TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200216392-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2020-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200216392-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERF2, PIEZO1, TERT TDP1 625/4885L3MBTL1 80/4885ENPP3 592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.