SCHEMBL22200035

SCHEMBL22200035

c1ccc(-c2nc3ccc4ccccc4c3nc2-n2c3ccccc3c3c4ccccc4c4c5ccccc5oc4c32)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
CSF1R P07333 1/20 0.34
PDGFRB P09619 1/20 0.34
KIT P10721 1/20 0.34
FLT3 P36888 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
TSHR P16473 3/20 0.32
PTGER1 P34995 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KDM4E B2RXH2 4/20 0.31
ALDH1A1 P00352 4/20 0.31
HPGD P15428 3/20 0.31
HSD17B10 Q99714 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22199929 0.98 MEN1 (0.33) MAPTMEN1KMT2ACSF1RPDGFRB
SCHEMBL22200028 0.96 MAPT (0.34) MAPTMEN1KMT2ACSF1RPDGFRB
SCHEMBL22200030 0.94 PTGER1 (0.33) MAPTMEN1KMT2ACSF1RPDGFRB
SCHEMBL22199969 0.89 LMNA (0.33) MAPTMEN1KMT2ACSF1RPDGFRB
SCHEMBL22199966 0.87 TSHR (0.33) MAPTMEN1KMT2ACSF1RPDGFRB
SCHEMBL16582318 0.87 HSD17B10 (0.40) MAPTMEN1KMT2ACSF1RPDGFRB
SCHEMBL22199930 0.86 MAPT (0.36) MAPTMEN1KMT2ACSF1RPDGFRB
SCHEMBL22199965 0.86 MAPT (0.37) MAPTMEN1KMT2ACSF1RPDGFRB
SCHEMBL22199797 0.85 LMNA (0.33) MAPTMEN1KMT2ACSF1RPDGFRB
SCHEMBL22200033 0.85 HSD17B10 (0.38) MAPTMEN1KMT2ACSF1RPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200216392-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2020-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200216392-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERF2, PIEZO1, TERT MAPT 2914/4885MEN1 1732/4885KMT2A 1788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.