SCHEMBL22200037

SCHEMBL22200037

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccc(-n5c6ccccc6c6c7ccccc7c7c8ccccc8n(-c8ccccc8)c7c65)cc4)n3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.44
ATM Q13315 2/20 0.44
KDM4E B2RXH2 1/20 0.44
AVPR1A P37288 1/20 0.40
KMT2A Q03164 5/20 0.38
IL1R1 P14778 1/20 0.38
MEN1 O00255 4/20 0.38
MAPT P10636 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HTT P42858 1/20 0.38
ABCG2 Q9UNQ0 1/20 0.38
HSP90AA1 P07900 1/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
RAB9A P51151 1/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17245563 0.98 L3MBTL1 (0.46) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL22200016 0.94 L3MBTL1 (0.42) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL20385320 0.93 L3MBTL1 (0.46) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL17123098 0.92 L3MBTL1 (0.42) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL26421339 0.92 KMT2A (0.43) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL17245560 0.92 L3MBTL1 (0.42) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL18667615 0.91 L3MBTL1 (0.41) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL14900857 0.91 L3MBTL1 (0.44) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL20385282 0.91 L3MBTL1 (0.47) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL20385225 0.91 L3MBTL1 (0.47) L3MBTL1ATMKDM4EAVPR1AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200216392-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2020-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200216392-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERF2, PIEZO1, TERT L3MBTL1 80/4885ATM 2798/4885KDM4E 1076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.